COG7

(redirected from component of oligomeric golgi complex 7)

COG7

A gene on chromosome 16p12.2 that encodes one of the 8 subunits of the conserved oligomeric Golgi (COG) complex, which is required for normal golgi morphology and localisation. COG7 mutations are associated with congenital disorder of glycosylation type IIe.
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References in periodicals archive ?
We obtained samples from patients with known glycosylation defects associated with the proteins that are encoded by these genes: mannosyl ([alpha]-1,6-)-glycoprotein [beta]-1,2-N-acetylglucosaminyltransferase (MGAT2); [beta]-1,4-galactosyltransferase 1 (B4GALT1); solute carrier family 35 (CMP-sialic acid transporter), member A1 (SLC35A1; other designation: CMP-sialic acid transporter); solute carrier family 35, member C1 (SLC35C1; other designation: GDP-fucose transporter); component of oligomeric Golgi complex 7 (COG7); and ATPase, H+ transporting, lysosomal V0 subunit a2 (ATP6V0A2).
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