complexed prostate-specific antigen


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complexed prostate-specific antigen

(kŏm-plekst′, kom′plekst″),

cPSA

A laboratory test that assays levels of prostate-specific antigen bound to alpha-1-chymotrypsin. The cPSA test is slightly more useful in the detection of prostate cancer than the simple PSA test but may not be as accurate as assessments of serum unbound or free PSA.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
A prospective study to evaluate the role of complexed prostate-specific antigen and free/total prostate-specific antigen ratio for the diagnosis of prostate cancer.
Comparison of two investigative assays for the complexed prostate-specific antigen in total prostate-specific antigen between 4.1 and 10ng/mL.
Complexed prostate-specific antigen for early detection of prostate cancer in men with serum prostate-specific antigen levels of 2 to 4 nanograms per milliliter.
Ratio of free or complexed prostate-specific antigen (PSA) to total PSA: which ratio improves differentiation between benign prostatic hyperplasia and prostate cancer?
Free and complexed prostate-specific antigen serum ratios to predict probability of primary prostate cancer and benign prostatic hyperplasia.
[4] Nonstandard abbreviations: PSA, prostate-specific antigen; ACT, [[alpha].sub.1]-antichymotrypsin; CaP, prostate cancer; MAb, monoclonal antibody; F-PSA, free prostate-specific antigen; T-PSA, total prostate-specific antigen; ESI-LC/ MS, electron spray ionization mass spectrometry coupled with liquid chromatography; hK2, human glandular kallikrein; hK1, human pancreatic /renal glandular kallikrein; HRP, horseradish peroxidase; FIBS, 10 mmol/L HEPES, pH 7.4, 150 mmol/L NaCl, 3.4 mmol/L EDTA; RU, resonance unit(s); PBS, phosphate-buffered saline; BSA, bovine serum albumin; EIA, enzyme immunoassay; F/T; ratio of free to total prostate-specific antigen; BPH, benign prostatic hyperplasia; and C-PSA, complexed prostate-specific antigen.
Free and complexed prostate-specific antigen: in vitro stability, epitope map, and development of immunofluorometric assays for specific and sensitive detection of free PSA and PSA-[[alpha].sub.1]-antichymotrypsin complex.