complete carcinogen

com·plete car·cin·o·gen

a chemical carcinogen that is able to induce cancer without provocation by a tumor-promoting agent introduced during therapy.

com·plete car·cin·o·gen

(kŏm-plēt' kahr-sin'ō-jen)
A chemical carcinogen that is able to induce cancer without provocation by a tumor-promoting agent introduced during therapy.
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References in periodicals archive ?
UV radiation (UVR) is a complete carcinogen that elicits a constellation of pathological events, including direct DNA damage, generation of reactive oxidants that peroxidize lipids and damage other cellular components, initiation of inflammation, and suppression of the immune response.
Apparently, asbestos plays a cocarcinogen role in lung cancer, with promoter-like activity and synergism with smoking, whereas in mesothelioma it acts as a complete carcinogen.
As regards oestradiol 17a, the SCVPH takes the view that the latest research findings indicate that the substance must be regarded as a complete carcinogen, as it is both tumour initiating and tumour promoting.
Epidemiological, clinical and biological studies have implicated that solar ultraviolet (UV) light is a complete carcinogen and repeated exposure can lead to the development of various skin disorders including melanoma and nonmelanoma skin cancers.
In liver cancer research with experimental animals, DEN is used either as a complete carcinogen or as an initiator in multistage models (5).

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