complementary DNA


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.
Related to complementary DNA: genomic DNA

DNA

 
complementary DNA (cDNA) (copy DNA (cDNA)) synthetic DNA transcribed from a specific RNA through the reaction of the enzyme reverse transcriptase.

com·ple·men·ta·ry DNA (cDNA),

1. single-stranded DNA that is complementary to messenger RNA;
2. DNA that has been synthesized from mRNA by the action of reverse transcriptase.

complementary DNA

n. Abbr. cDNA
Single-stranded DNA synthesized in the laboratory using messenger RNA as a template and the enzyme reverse transcriptase.

com·ple·men·ta·ry DNA

(cDNA) (kom'plĕ-men'tăr-ē)
1. Single-stranded DNA that is complementary to messenger RNA.
2. DNA that has been synthesized from mRNA by the action of reverse transcriptase.

complementary DNA

A sample of DNA that has been produced from MESSENGER RNA after conversion into double-strand DNA.

complementary DNA

see CDNA.
References in periodicals archive ?
Previous work indicated that the single strand of the target DNA sequence, and not the complementary DNA strand, preferentially binds to the nanoprobe (10, 11).
32]P-end labeling and annealed to the complementary DNA (see Figure 1A for nucleotide sequences).
Complementary DNA was amplified by nested polymerase chain reaction (PCR) by using primers from the small (S) RNA segment of C-CHFV (4).
In spotted microarrays, slides carrying spots of target DNA are hybridized to fluorescently labeled complementary DNA (cDNA) from experimental and control cells and the arrays are imaged at two or more wavelengths.
By adding fluorescent labels to the complementary DNA, researchers can estimate the degree of cytokine expression by the brightness of each dot.
On the basis of types: Oligonucleotide DNA Microarrays (oDNA) and Complementary DNA Microarrays (cDNA)
These units are subsequently targeted to bind monoclonal DNA clusters in the flow cell of an Illumina sequencer by complementary DNA hybridization.
Results showed that the produced biosensors had more desirable selectivity in DNA crossing than complementary DNA in comparison with non-complementary DNA series.
Supreme Court ruled that companies cannot patent isolated human genes, but can patent human-engineered DNA molecules, including so-called complementary DNA or cDNA.
DNA polymerase then produces complementary DNA strands in the extension step.
They then used this to create a complementary DNA sequence to identify the genes potentially involved in glue creation.
Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA [Erratum in: Science 1989;245:1437].

Full browser ?