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Biochemistry Relating to the inhibition of enzyme activity that results from an alternate compound binding reversibly to the site on an enzyme where the substrate would normally bind.
the relationship in which two or more entities contend for association with another.
compounds, usually structural analogs of the substrate, that bind reversibly to an enzyme and deny the substrates access to the active site.
competitive protein binding
binding proteins occur naturally and have affinity for other substances, for example sex hormone steroid-binding globulin. The property is made use of in the assay of such substances in body fluids and tissues. Called also CPB.
competitive protein binding assay
see competitive protein binding (above).
a technique utilizing isotope labeled antigen that competes with unlabeled antigen for union with specific antibody. A very sensitive assay, commonly used in detecting trace amounts of drugs.