comparative effectiveness research


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comparative effectiveness research

Any head-to-head study of alternative solutions to managing a disease, esp. when such a study examines a broadly representative population of patients and follows them for a long enough time to determine meaningful outcomes. Its goal is to identify which treatment produces the best clinical outcomes for most patients, rather than which is better than a placebo or which influences a laboratory test or other surrogate marker without having an impact on the actual health or longevity of patients.
See also: research
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Comparative effectiveness research, genomics-enabled personalized medicine, and rapid learning health care: a common bond.
"The Pragmatist's Guide to Comparative Effectiveness Research." Journal of Economic Perspectives 25 (2): 27 46.
While sympathetic to the economist's point of view, the authors argue that comparative effectiveness research "still holds promise." First, it sidesteps objections from policy makers and voters to the idea of rationing access to health services based on cost effectiveness.
The distinguishing feature of PubMed Health is the inclusion of comparative effectiveness research. According to AHRQ, "comparative effectiveness research is designed to inform health-care decisions by providing evidence on the effectiveness, benefits, and harms of different treatment options" [9].
COORDINATING COUNCIL FOR COMPARATIVE EFFECTIVENESS RESEARCH, U.S.
These markets are limited by heightened pricing pressure exerted on manufacturers by hospitals and group purchasing organizations and the increased scrutiny of the devices and procedures due to cost containment initiatives and the introduction of comparative effectiveness research.
Electronic data resources, clinical leadership, data and statistical support, and cultural reorganization of priorities are needed for effective comparative effectiveness research, he continued.
The companies said that the research, which will include prospective and retrospective observational studies on disease states as well as comparative effectiveness research, will analyse how medicines and treatments already on the market are working in a number of disease areas, with a special emphasis on chronic illnesses.
Brody and Light recommend some actions: restrict writing usage guidelines to groups free of commercial conflicts of interest; independently fund and design trials focused on safety and efficacy; and create a neutral agency (e.g., a branch of the National Institutes for Health) to conduct drug trials, including comparative effectiveness research to improve evidence-based prescribing.
The Effective Health Care Program funds individual researchers, research centers, and academic organizations to work together with the AHRQ to produce effectiveness and comparative effectiveness research for clinicians, consumers, and policymakers.
Comparative Effectiveness Research: What Every Oncology Nurse Needs to Know
As the nation moves forward with the implementation of healthcare reform, NPC s research provides policy makers and implementers with keen insight on comparative effectiveness research and health-and-wellness issues, Bailey said.

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