common antigen


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com·mon an·ti·gen

cross-reacting antigen (epitope); a common antigen that occurs in two or more different molecules or organisms.

com·mon an·ti·gen

(kom'ŏn an'ti-jen)
Cross-reacting antigen (epitope), a common antigen that occurs in two or more different molecules or organisms.
Synonym(s): heterogenic enterobacterial antigen.
References in periodicals archive ?
The diagnosis was made on microscopic features and positivity with Leucocyte common antigen.
Additionally, the RS-like cells also expressed CD45 (leukocyte common antigen), CD20, PAX-5, CD10, BCL-6, and BCL-2 (Figure 2, D through F).
Immunohistochemical staining for CD45 (leukocyte common antigen), CD5, Melan-A, S100 protein, desmin, HMB-45, CD35, CD21, CD10, EBV, CD34, glypican 3, podoplanin (D2-40), CD31, c-kit, estrogen receptor, progesterone receptor, smooth muscle antigen, calretinin, and CD1a was negative.
Leukocyte common antigen (CD45) is often expressed along with various T-cell-specific markers, although null-cell immunophenotype forms also exist in spite of having T-cell genotypes.
CD68, leukocyte common antigen, and pancytokeratin were negative (Figure 3, B).
(2,13) Even for a common antigen evaluated in a particular tissue, ER in breast specimens for example, data conflict, with a minimum of 1 hour, (19) 6 hours, (14,17) or 24 hours (6,11) in fixative required for uniform and reproducible immunostaining.
For data analysis, most laboratories use a "gating" system in which predetermined combinations of cellular characteristics, for example, intrinsic light scatter properties combined with level of CD45 (leukocyte common antigen) expression, are used to define populations of cells that are then characterized with respect to expression of specific antigens.
(16) Other stains like [alpha]-fetoprotein, human chorionic gonadotropin, carcinoembryonic antigen, S100 protein, vimentin, epithelial membrane antigen, leukocyte common antigen, neuron-specific enolase, and human placental lactogen are not demonstrable in spermatocytic seminoma.
Immunohistochemistry according to the avidin-biotin-peroxidase technique (10) using antibodies against vimentin (monoclonal, 1:400; Dako Corporation, Carpinteria, Calif), leukocyte common antigen (monoclonal, 1:200; Dako), UCHL-1 (monoclonal, 1:200; Dako), CD3 (monoclonal, 1:200; Dako), CD20 (monoclonal, 1:200; Dako), CD30 (monoclonal, 1:20; Dako), EMA (monoclonal, 1: 10 000; Dako), and S100 protein (polyclonal, 1:200; Dako) was performed on 4-[micro]m-thick sections of paraffin-embedded tissue blocks from both breast and axillary lesions.
The cells stained negatively for desmin, S100 protein, glial fibrillary acidic protein, keratin, epithelial membrane antigen, CAM 5.2, HMB-45, leukocyte common antigen, factor VIII-associated antigen, c-Kit, and CD34.
Representative sections of the surgical resection specimen were fixed in formalin, embedded in paraffin, and stained with hematoxylin-eosin, as well as immunohistochemically using a diaminobenzidine method, with antibodies directed against S100 protein (used here as a marker for cells of chondrocytic origin), CD45 (leukocyte common antigen), and CD68 (a macrophage-monocyte marker).
Leukocyte common antigen (prediluted, Dako) stain demonstrated membranous staining pattern of the histiocytic cells and engulfed lymphocytes.

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