comedonecrosis

com·e·do·ne·cro·sis

(kom'ē-dō-nek-rō'sis),
A type of necrosis occurring with glands in which there is central luminal inflammation with devitalized cells, usually occurring in the breast in intraductal carcinoma.
[comedo + necrosis]
References in periodicals archive ?
Florid LCIS has been referred to in the literature as macroacinar lobular intraepithelial neoplasia (18) and LCIS with comedonecrosis (19) The designation florid is applied to cases of LCIS with the marked ductal and lobular expansion by LCIS cells of low to intermediate nuclear grade (Figure 4, B).
Current Concepts in Diagnosis, Molecular Features, and Management of Lobular Carcinoma In Situ of the Breast With a Discussion of Morphologic Variants
Points are scored for the histological pattern, tumour cellularity, comedonecrosis, vascular or capsular invasion, Ki-67 labeling, and catecholamine subtype.
Recurrent, bilateral, and metastatic pheochromocytoma in a young patient with Beckwith-Wiedemann syndrome: a genetic link?
Lesions that show marked nuclear pleomorphism, with or without apocrine features and comedonecrosis are referred as pleomorphic LCIS (PLCIS).
Categorization of insitu breast carcinoma based on morphology and immunohistochemistry
A): Dynamic contrast- enhanced image disclosed a ring-like tumor focus; B): Enhancement rate 230%; C): Ascending enhancing mode and dynamic contrast-enhanced curve; D and E): Optical microscopic observation showed comedonecrosis (white arrow) and fibrosis (black arrow) (HEA-100).
Clinical pathologies of breast cancer in the elderly and youths and their prognosis
Comedonecrosis and a young age at diagnosis, reported by others to be also associated with histological upgrade, were not found significant in our study [25, 28].
Sentinel lymph node biopsy should be included with the initial surgery for high-risk ductal carcinoma-in-situ
They feature large ducts with solid, papillary, and comedonecrosis areas (figure 1).
Salivary duct carcinoma
17) The architectural pattern of IDCP includes solid growth, a dense cribriform or micropapillary pattern with marked nuclear atypia, and occasional comedonecrosis.
Biomarker, Molecular, and Technologic Advances in Urologic Pathology, Oncology, and Imaging
A high number of mitotic figures is present, and the tumor shows extensive coagulative necrosis with areas of central comedonecrosis.
Clinical manifestations of sinonasal undifferentiated carcinoma
2) The most commonly used contemporary definition of IDC-P is by Guo and Epstein, (52) requiring an intraductal growth with either: (1) solid pattern; (2) dense cribriform morphology, defined as greater than 70% epithelium as opposed to lumens; or (3) loose cribriform and/or micropapillary lesions with either marked nuclear atypia (6X normal) or comedonecrosis (Figure 3, E and F).
Prostate Cancer Grading: A Decade After the 2005 Modified Gleason Grading System
True tumor comedonecrosis suggests malignancy (figure 2, B).
Parathyroid carcinoma
Leal et al (18) classified apocrine DCIS into low, intermediate, and high grade based on nuclear criteria and the presence of comedonecrosis.
Atypical Apocrine Adenosis: Diagnostic Challenges and Pitfalls
Medical browser ?
Full browser ?