Isotretinoin has both an anti-inflammatory effect and comedolytic
This was a "notable" finding, they wrote, "because benzoyl peroxide and tretinoin are known as comedolytic
, but tretinoin is not typically thought of as having antibacterial properties like benzoyl peroxide."
SA also has comedolytic
and antiinflammatory action, making it suitable for both noninflammatory and inflammatory acne lesions.7
BP is an antibacterial agent, with mild comedolytic
properties, and it often is added to topical antibiotic therapy to increase effectiveness and reduce the development of resistance.
Sulphur: it is both comedogenic and comedolytic
. Rarely used because of its smell.
They have very good keratolytic and comedolytic
Isotretinoin To evaluate skin penetration All trans To produce comedolytic
retinoic acid effect and reduce skin irritation.
They are also comedolytic
and have intrinsic anti-inflammatory effects, thus targeting two pathogenic factors in acne.
This is due to the comedolytic
effect of the medication; with continued use the skin adapts with noted improvement in skin appearance and less irritation.
Salicylic acid, found in a number over-the-counter cleansers, has both anti-inflammatory and mild comedolytic
It has keratolytic, fungicidal and bactericidal and comedolytic
Topical BPO has antimicrobial, keratolytic and comedolytic
properties, with no fear of antibiotic resistance.