comedocarcinoma


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Related to comedocarcinoma: comedonecrosis

com·e·do·car·ci·no·ma

(kō-mē'dō-kar'si-nō'mă),
Form of carcinoma of the breast or other organ in which plugs of necrotic malignant cells may be expressed from the ducts.

comedocarcinoma

[kom′idōkär′sinō′mə] pl. comedocarcinomas, comedocarcinomata
Etymology: L, comedere, to consume; Gk, karkinos, crab, oma, tumor
a malignant intraductal neoplasm of the breast, in which the central cells degenerate and may be easily expressed from the cut surface of the tumor. Growth confined to the mammary ducts carries a better prognosis than do invasive breast lesions.

com·e·do·car·ci·no·ma

(kom'ĕ-dō-kahr-si-nō'mă)
Form of carcinoma of the breast or other organ in which plugs of necrotic malignant cells may be expressed from the ducts.

comedocarcinoma

An ADENOCARCINOMA of the breast in which the milk ducts are filled with cancer cells forming COMEDO-like bodies.
References in periodicals archive ?
Figure 6: Comedocarcinoma with squamous differentiation.
For example, in a metastatic lesion, the presence of solid nests and trabeculae composed of tumor cells with limited nuclear pleomorphism, punctate areas of necrosis suggestive of comedocarcinoma, or trabeculae composed of small hyperchromatic tumor cells strongly suggests the possibility of a breast origin, particularly in a female patient (9) (Figure 4, A through D).
In contrast to more typical cases of comedocarcinoma, these tumor cells lacked apocrine features, specifically abundant granular cytoplasm, but instead had scant cytoplasm that was focally clear.