combination chemotherapy


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Related to combination chemotherapy: antitumor, Chemotherapeutic agent

combination chemotherapy

chemotherapy using more than a single drug to exploit the varying levels of toxicity for the patient's benefit.

com·bi·na·tion che·mo·ther·a·py

(kom-bi-nāshŭn kē-mō-thāră-pē)
Therapy using more than a single drug to exploit the varying levels of toxicity for the patient's benefit.
References in periodicals archive ?
Cyclical combination chemotherapy and gonadal function.
A single institution experience of 30 cases in the combination chemotherapy era.
In our patient, however, combination chemotherapy with oral S1 and gemcitabine had no therapeutic effect.
meta-analysis [10] and ITACA trial [11] and then analyzed efficacy of adding bevacizumab to first-line chemotherapy or the most used combination chemotherapy of mCRC, compared with chemotherapy alone.
In order to further investigate the association between gene expression in peripheral blood and the efficacy of gemcitabine and carboplatin combination chemotherapy, we collected a series of peripheral blood samples and tumor tissue from Chinese advanced NSCLC patients treated with gemcitabine plus platinum.
In addition, in the maintenance paclitaxel 1 (MANTA 1) study, 255 metastatic breast cancer patients who received a first-line anthracycline / paclitaxel combination chemotherapy followed by a paclitaxel maintenance regimen had a median time to progression (MTTP) that was not significantly better than that of the control group [8 months in the sequential paclitaxel maintenance therapy group vs 9 months in the control group (P = 0.817)], and the median overall survival rates were 28 and 29 months (P = 0.547).
Sledge (oncology, Stanford U.) and Baselga (Memorial Sloan-Kettering Cancer Center) draw together cancer, biostatistics, pathology, and other medical specialists from the US, Canada, and Poland for six chapters that examine targeted therapies in breast cancer, with a focus on chemoprevention strategies, drug resistance, biomarkers, combination chemotherapy, angiogenesis inhibition, and pharmacogenomics in the context of clinical efficacy.
Again, she was challenged with combination chemotherapy containing doxorubicin and vincristine for 4 cycles, with no clinical benefit, and palliative EBRT was offered to problematic lesions of the vulva and left foot.
Subsequently, combination chemotherapy with ifosfamide, epirubicin, and cisplatin and with hydroxyurea, DTIC, and etoposide (VP-16) was given.
Improved survival with combination chemotherapy. Clin Orthop Relat Res.
(34) Multi-agent combination chemotherapy regimens may have synergistic toxicity, and the specific contribution of each agent is often difficult to determine.
Currently up to 35% of patients with Hodgkin lymphoma relapse or become refractory after initial treatment, which typically involved at least two regimens of combination chemotherapy with high-dose chemotherapy and stem cell transplant.