colonocyte

colonocyte

(kŏ-lŏn′ŏ-sīt) [″ + ″]
An endothelial cell of the large intestine.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
In laboratory experiments, acute stress has been shown to act on the GI tract by inducing changes in colonocyte differentiation and decreased expression of mRNA encoding tight junction proteins.
Caption: Figure 3: HOX gene expression during colonocyte differentiation.
Hong et al., "An increase in reactive oxygen species by dietary fish oil coupled with the attenuation of antioxidant defenses by dietary pectin enhances rat colonocyte apoptosis," The Journal of Nutrition, vol.
Rombeau, Butyrate and the Colonocyte. Dietary Fiber in Health and Disease, Springer, Berlin, Germany, 1997.
Preliminary characterization of jejunocyte and colonocyte cell lines isolated by enzymatic digestion from adult and young cattle.
Colonocyte tests also share the same advantage as FOBTs with respect to being non-invasive, relatively inexpensive, and relatively easy to perform.
Thus prevention is key, because it is hard to rebuild the colonocyte population once ulcerative colitis has begun.
Butyrate plays many well-documented roles in the intestine including serving as the primary fuel source for the colonocyte, regulating water and electrolyte absorption and gene expression, providing support of the epithelial barrier, modulating visceral sensitivity and intestinal motility, and ameliorating mucosal inflammation and oxidative stress [21].
Multiple mechanisms have been proposed, including the overgrowth with a single pathogenic agent, the local production of toxic metabolites, and a modification of the local microenvironment with deleterious consequences for colonocyte metabolism and mucosal perfusion [7, 10].
DHA alters colonocyte mitochondrial membrane composition and function to create a pathway for butyrate and other metabolites to induce apoptosis.