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Related to colonic crypt: crypts of Lieberkühn, intestinal gland


Relating to the colon.
Farlex Partner Medical Dictionary © Farlex 2012


adjective Referring to the colon.

noun See Colon therapy.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Relating to the colon.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Patient discussion about colonic

Q. How is colon cancer diagnosed?

A. thank you lamsophie, great answer...

Q. how successful is the treatment of removing the colon? Are there any people who have had their colons removed successfullly? What other treatment options are there and how successful are they?

A. colon removal is a treatment for various situation, usually a last resort treatment...when anything else just wouldn't or couldn't work.
it's "success" as a treatment depends on the cause. i can tell you that this is the area that absorbs B12 and bile and most of the water, so expect a shortage of that three. in the water and bile case- expect watery stool...
sorry all that doesn't seem such a nice state but when Dr. come to the point they have to do it- there must be a good enough reason.

Q. Is colon cancer hereditary? My uncle died of colon cancer and as I've been having some unexplained problems these days- of vomiting etc I'm really afraid I may have it as well. Is it hereditary? What are the first symptoms?

A. Thank you Bianca for your answers! helped a lot...this is a great site!

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References in periodicals archive ?
Normal colonic crypts consist of mainly three types of cells based on their location in the crypt.
Bacterial species found within the crypt, as identified by 16S sequencing, and fluorescent in situ hybridization (FISH) of murine colonic crypts, indicate the predominance of bacteria capable of aerobic metabolism, including species of Acinetobacter and Proteobacteria [5].
CDH17 (A) and CDX2 (B) stained full-length colonic crypts. C, CK20 stained the upper half of colonic crypts.
Our findings show that shortening of colonic crypts in bowel segments excluded from the fecal stream is an early event in the development of diversion colitis in our murine model.
Dynamic balance between cell production at the base and cell death at the surface of the colonic crypts is precisely regulated by a number of physiological endogenous factors.
In a 1973 study by Kaye et al, (9) the authors found that when compared to the normal progressive maturation of cells in colonic crypts, "the hyperplastic epithelium exhibits a similar progression, the primary difference being that most of the morphological features of maturing and mature cells are found either lower in the crypt or in exaggerated form at the same level of the crypt when compared with normal mucosa in the same colon." A year later, Hayashi et al (10) used electron microscopy to show that the cells on the surface of hyperplastic polyps looked hypermature and demonstrated a decreased rate of migration in cells from base to surface when using autoradiography.
In at least 70% of cases, the colonic crypts associated with perineuriomas are lined by serrated epithelium similar to that of microvesicular hyperplastic polyps (25, 27) (Figure 3).
Acute ischemic lesions of the colon show superficial mucosal necrosis that may spare the deeper portions of the colonic crypts. The remaining crypts typically have a withered or an atrophic appearance.
The tumor cells fill the lamina propria and spread apart the colonic crypts (Figure 1, A and B).
The belief that some neoplastic precursor lesions in IBD may show basal crypt dysplasia, with surface maturation, is not surprising given that precursor stem cells and transient amplifying cells have been identified in the bases of the colonic crypts, as seen in BE, and these cells are presumed to be most susceptible to neoplastic alteration.