colon polyp

colon polyp

Gastroenterology A hereditary or acquired pedunculated neoplasm arising from the colonic mucosa; small CPs are usually benign, but may become malignant; like colorectal CA, CPs may present with occult bleeding. See Polyp, Colorectal cancer.
Colon polyp
Acquired polyps Adenomatous or tubular–villous in morphology, ↑ frequency with age; although often asymptomatic, larger polyps are often announced by bleeding or changed bowel habits; if very large, APs may form a leading 'front' of an intussusception; distinction between adenomatous polyps–'tight' round glands and villous adenomas–finger-like fronds of elongated glands has little practical importance–both have malignant potential; periodic colonoscopy and polypectomy yields a 3-fold ↑ in subsequent cancer; hyperplastic polyps are also acquired but are non-neoplastic
Hereditary polyps
• Familial adenomatous polyposis A premalignant, AD condition presenting in early adulthood with 100s to 1000s of colonic polyps, related to a loss of the normal repression of DNA synthesis in the entire colonic epithelium; adenocarcinoma occurs in 70–100% of Pts, prevented by prophylactic colectomy
• Gardner syndrome A rare AD condition with premalignant polyps of the entire GI tract, which is identical to FAP, but has, in addition, extraintestinal tumors; most Pts develop colon carcinoma; other neoplasms in GS Pts include bile duct carcinoma, osteomas of mandible, skull, and long bones, soft tissue tumors–fibromas, lipomas, sebaceous cysts, and rarely, thyroid and adrenal gland cancers
References in periodicals archive ?
(11) In another study, Uchiyama et al observed that 1 out of 7 solitary rectal polyp was adenoma and 1 out 10 solitary sigmoid colon polyp were associated with adenomatous changes.
Colon polyp autoamputation: case presentation and literature review
Burke, MD, Vice Chair of Cleveland Clinic's Department of Gastroenterology & Hepatology and Director of the Center for Colon Polyp and Cancer Prevention.
Similar accuracy of surveillance recommendations with and without using polyp pathology, as seen in our study supports American Society of Gastrointestinal Endoscopy's PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) [11] to promote endoscopic technologies that aid in optical diagnosis of diminutive colon polyp histology.
Adenomas are a type of colon polyp that is considered a precursor for invasive colorectal cancer (CRC).
A colon polyp is an abnormal growth of tissue along the lining of the colon.
"Risk factors common to both coronary artery disease and colorectal tumors (benign and malignant) include physical inactivity; diets that are high in saturated fats and processed meats and low in fresh fruits, vegetables, and grains; obesity; aging; and smoking," says Carol Burke, MD, director of the Center for Colon Polyp and Cancer Prevention at Cleveland Clinic.
The company cites a clinical study that shows that 1,200 mg a day of calcium, the amount in two tablets daily of Caltrate Colon, helps reduce the risk of colon polyp recurrence.
While these researchers reported no change in colon polyp recurrence in those who took a standard dose (325 mg), a second study of 517 patients found that this higher dose made polyp recurrence 35% less likely than for patients in a second, placebo group.
Dealers said Wednesday's announcement by the government that Prime Minister Junichiro Koizumi had surgery the same day to remove a colon polyp had only a limited impact on trading as the government said the polyp was benign.
Aickin, "The difference in colon polyp size before and after removal," Gastrointestinal Endoscopy, vol.