colocalization


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colocalization

(kō″lō″kăl-ĭ-zā′shŭn) [″ + ″]
The consistent presence of two molecules at a single cellular site, as evidenced by digital or fluorescent imaging techniques.
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References in periodicals archive ?
As part of a recent examination of GAB A-dopamine colocalization in pulmonates (Vaasjo et al., 2018; see Colocalization of GABA and Dopamine), we confirmed the presence of a GABA-like epitope in neurons in the subesophageal ganglia of Lymnaea (Hatakeyama and Ito, 2000; Fig.
This result is in agreement with the high colocalization of PRLR with both LHR and 3[beta]-HSD detected in luteal cells of midgestating animals, which suggests a possible role of PRL during pseudoovulation and luteinization of L.
Retinas from P18 mice after oxygen-induced ischemic retinopathy displayed increased Flt3 staining in the inner retina with colocalization of GSA-Lectin on the retinal surface in new vessels (Figure 1(B)).
While colocalization with cortical pyramidal cells is less common, this does occur and is more often observed in the visual cortex than in secondary motor areas [18].
In fact, colocalization of DJ-1 and NDUFS3 has been shown in NIH3T3 and HEK293 cells [11].
Phagosome-lysosome fusion was evaluated by the colocalization of both markers, and the markers were described in materials and methods (Fig.
Golgi apparatus-Enamelysin- Amelogenin Colocalization. After labeling, through the images from confocal-microscope, it is observed in the figure 1: A) a label is observed using as a first antibody Anti-Golgi (molecular probes) second antibody: Alexa Fluor 488 Secondary Antibody (Molecular Probes) (green) the enamel organ can be found on the top right side, on the left side of the dental papilla.
The involvement of trans-Golgi/endosomal fusion in the extension and closure of isolation membranes was confirmed by the colocalization of mannose-6-phosphate receptors (a trans-Golgi/late endosomal marker) and syntaxin 7 (a late endosomal marker) with autolysosomes in etoposide-treated Atg5-deficient MEFs.
Thus, its colocalization with CEA increases the binding of cells to fibronectin and activates downstream signals through the regulation of PI3K and AKT activity [93].
(1,4,5) Immunofluorescence has a higher sensitivity and allows for the colocalization of several antigens labeled by different fluorophores compared with immunohistochemistry.