These include complement components, collectins
, ficolins, and pentraxins.
Heritability estimates for the constitutional levels of the collectins mannan-binding lectin and lung surfactant protein D.
MBL, another key component of the innate immune system, is a soluble protein of the collectin family that binds to microbial surfaces and promotes phago-opsonization directly and indirectly by activating the lectin complement pathway.
Studies have been undertaken to evaluate the association between endometrial and placental expression of immunoregulatory molecules such as collectins
and recurrent spontaneous abortions and pre-term labor.
Collectins and ficolins: humoral lectins of the innate immune defense.
The human collectin, mannose-binding lectin (MBL) is one of the important components of innate immunity (1,2).
Although collectins can be immunomodulatory for adult alveolar macrophages (Hickling et al.
Innate immune collectin surfactant protein D enhances the clearance of DNA by macrophages and minimizes anti-DNA antibody generation.
We hypothesized that the degree of glycosylation of influenza viruses is inversely related to virulence in a naive host due to glycosylation allowing easier clearance by collectins
Among such proteins are lung surfactant proteins A and D, also known as collectins
, or collagen-like domain and calcium-dependent lectin domain proteins (Crouch and Wright 2001).