collagenases


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Related to collagenases: Interstitial collagenase

collagenases

Enzymes that can break down COLLAGEN and gelatin.
References in periodicals archive ?
Studies on neutrophil collagenase and MMP-18 in clear cell renal cell carcinoma did not demonstrate any increase in their activity in primary tumour tissue or metastases as compared to normal tissue [3,32].
The proposed noninflammatory mechanisms include defective collagenase activity due to decreased uptake of folic acid, blockage of aldosterone synthesis in adrenal cortex, and consequent feedback increase in adrenocorticotropic hormone level and upregulation of keratinocyte growth factor.
In the present study, we compared the selectivity of SalA on collagenases and gelatinases which are two kinds of MMPs that play important roles in aortic remodeling.
Tetracycline inhibition and the cellular source of collagenase in gingival crevicular fluid in different periodontal diseases: a review article.
To facilitate the mobility of these cells, an enzyme needed to break down collagen, which is the largest component of the extracellular matrix, called collagenase (matrix metalloproteinases/ MMP), such as MMP-1, -8, and -13.
Synergistic collagenase expression and cartilage collagenolysis are phosphatidylinositol 3-kinase/Akt signalingdependent.
However, during remodeling of the connective tissue in such processes as wound healing and metastasis, collagen becomes susceptible to cleavage by collagenases.
The formulation, made up of two collagenases produced by the bacterium Clostridium histolyticurn, is injected into the cord at 4-week intervals, for a maximum of three injections, according to the manufacturer, Auxilium Pharmaceuticals Inc.
The formulation, made up of two collagenases naturally produced by the bacterium Clostridium histolyticum, is injected into the cord at 4-week intervals, for a maximum of three injections), according to the manufacturer, Auxilium Pharmaceuticals Inc.
Despite the currently available knowledge base, some studies performed on gelatinases and collagenases in serum do not address the concerns raised by reports of pitfalls and misinterpretations linked to preanalytical aspects of blood processing.
2-4) Secreted-type MMPs can be classified into 6 subgroups according to their substrate specificity and structural differences (2): (1) collagenases, including tissue collagenase (MMP1), neutrophil collagenase (MMP8), and collagenase 3 (MMP13); (2) gelatinases, such as gelatinase A (MMP2) and gelatinase B (MMP9); (3) stromelysins, including stromelysin 1 (MMP3) and stromelysin 2 (MMP-10); (4) matrilysins, such as matrilysin 1 (MMP7) and matrilysin 2 (MMP26); (5) furin-activated MMPs, including stromelysin 3 (MMP-13) and epilysin (MMP 28); and (6) other MMPs such as metalloelastase (MMP12), MMP19, enamelysin (MMP-20), MMP21, and MMP-27.
The remodeling progresses immediately after myocardial damage with an increased level of collagenases (Janicki et al.