collagen disease


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Related to collagen disease: Scleroderma, Connective tissue disorder

col·la·gen dis·ease

, collagen-vascular disease
a group of generalized diseases affecting connective tissue and frequently characterized by fibrinoid necrosis or vasculitis; in some collagen diseases, auto-immunization, particularly antinuclear antibodies, has been shown and circulating immune complexes are found. The term is not entirely acceptable because there is no evidence that collagen is primarily involved; "collagen" was once synonymous with "connective tissue" rather than describing a specific fibrinous protein in that tissue.
See also: connective-tissue disease.

col·la·gen dis·ease

, collagen-vascular disease (kol'ă-jen di-zēz', kol'ă-jen-vas'kyū-lăr)
A group of generalized diseases affecting connective tissue and frequently characterized by fibrinoid necrosis or vasculitis; in some collagen diseases, autoimmunization, particularly antinuclear antibodies, has been shown and circulating immune complexes are found. The term is not entirely acceptable because there is no evidence that collagen is primarily involved; "collagen" was once synonymous with "connective tissue" rather than describing a specific protein in that tissue.
See also: connective-tissue disease

collagen disease

A term formerly, and erroneously, applied to such conditions as rheumatic fever, ankylosing spondylitis, polyarteritis nodosa, lupus erythematosus, rheumatoid arthritis and dermatomyositis but now applied to those known to be caused by defects in the chemical structure of collagen and its distribution and quantity. The collagen diseases include solar and senile elastosis, SCURVY, STRIAE, KELOIDS, PEYRONIE'S DISEASE, PSEUDOXANTHOMA ELASTICUM and the EHLERS-DANLOS SYNDROME.

col·la·gen dis·ease

, collagen-vascular disease (kol'ă-jen di-zēz', kol'ă-jen-vas'kyū-lăr)
Generalized disorder affecting connective tissue.
References in periodicals archive ?
AECAs are considered to be critical, especially for vascular lesions in collagen diseases, but most are directed against molecules localized within the cell and not expressed on the cell surface.
This lady also had a significant peripheral eosinophilia unresponsive to anti parasitic chemotherapy, a normal bone marrow biopsy aspirate and p-ANCA, which was non reactive thus ruling out parasitic infestations, collagen diseases such as Churgh-Strauss Syndrome and haematological malignancies.
She was amazed to hear that the Gerson Therapy is very effective in overcoming collagen diseases, such as rheumatoid arthritis.
In addition to its use in fetal medicine, dexamethasone is used for a whole host of indications from endocrine and rheumatic disorders to collagen diseases and cerebral edema.