colistimethate

colistimethate

 [ko-lis″tĭ-meth´āt]
an antibiotic that is a colistin derivative; the sodium salt is used in treatment of infections.
References in periodicals archive ?
An FDA report said that among the top 18 drugs requested in 2013 and 2014, the Colistimethate Na 1 M Unit vial led the list with a total of 44,770 units.
In vitro assessment and multicenter cohort study of comparative nephrotoxicity rates associated with colistimethate versus polymyxin B therapy.
M2 PHARMA-December 12, 2018-Non-Cystic Fibrosis Bronchiectasis FDA Grants "Fast-Track" and "QIPD" to Zambon for Colistimethate Sodium Powder for Nebulizer Solution Delivered by the I-neb AAD System
Pharmacokinetics of colistin and colistimethate sodium after a single 80-mg intravenous dose of CMS in young healthy volunteers.
Either international units or milligrams of the sodium salt colistimethate (the inactive prodrug) may be used, and to confuse matters further, colistin base activity (CBA) in milligrams may also be used to define the dose.
Colistin (colistimethate sodium colistin(r)) was used in a dose of 25,000 units/kg/day intravenously in 2-3 divided doses and/or 125,000 units twice daily as aerosolised therapy.
In another multicentre, retrospective cohort study, comparison of nephrotoxicity rates between colistimethate sodium (n = 121) and polymyxin B (n = 104) was performed by Phe et al.
Colistimethate sodium was administered as recommended in the literature in three equal doses of 5 mg/kg per day, 12 hours after a single 5 mg/kg loading dose.
Of note, polymyxin-containing batches from commercial origin can be used, but the colistimethate sulfate powder, a therapeutic prodrug of colistin, cannot be used.
Xellia is a supplier of vancomycin and colistimethate sodium which together combat multi-drug resistant bacterial infections across Gram-positive and Gram-negative species.
Efficacy and safety of colistin (colistimethate sodium) for therapy of infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii in Siriraj Hospital, Bangkok, Thailand.