cold nodule

cold nod·ule

a thyroid nodule with a much lower uptake of radioactive iodine than the surrounding parenchyma; about one in four prove to be malignant.

cold nodule

Imaging A focus of ↓ radioisotope uptake on a 123I or 99mTc scintillation scan of the thyroid, seen in cystic or solid, often nonfunctional lesions; when the mass is solid by ultrasound, a biopsy is warranted as most carcinomas are cold nodules. Cf Hot nodule, Warm nodule.

cold nod·ule

(kōld nod'yūl)
A thyroid nodule with a much lower uptake of radioactive iodine than the surrounding parenchyma; about one in four proves to be malignant.
References in periodicals archive ?
(a) whole body scan performed after treatment with radioactive iodine or surgery; (b) focal uptake with centrally hypoactive foci before treatment; (c) hot nodule detected post-treatment with radioactive iodine; (d) patient was treated with radioactive iodine, achieved euthyroidism, and became negative for TRAb; a hot nodule was detected on follow-up on both ultrasound and nuclear scan; (ab) cold nodule before treatment and hot nodule after treatment with radioactive iodine.
Role of fine needle aspiration cytology (FNAC) in a cold nodule of thyroid and its comparison with histopathology.
6b, blue line), while minimum frost flower temperatures at the cold nodule locations decreased toward the air temperature throughout the overnight period of frost flower growth (Fig.
Economic and an accurate procedure used in the diagnosis of thyroid Lesions, particularly in the presence of cold nodule [1].
Thirteen respondents said that a dominant nodule would lead to an FNA, and 11 respondents said that a cold nodule would be a criterion for an FNA.
While her thyroid uptake scans previously identified a cold nodule in the lower right thyroid lobe, her surgical pathologic specimen of the left thyroid lobe identified the anaplastic carcinomic tissue while her right thyroid nodule was negative for anaplastic disease.
[12] Thyroid isotope scan using technetium detect hot or cold nodule. Hot nodules are functioning and usually benign, but cold nodules are nonfunctioning and around 20% may be malignant.
A hot nodule is almost always benign however a cold nodule requires further diagnostic evaluation.
(2) Radioactive iodine [sup.131] I scintigraphy will show a poorly defined cold nodule. (1) Chest x-rays may demonstrate a lung metastasis or a deviation or narrowing of the trachea.
cold nodule) are considered as risk factors for thyroid malignancy.
Most common form of thyrotoxicosis was Graves\' disease, with diffuse toxic goiter affecting 269 (53%) patients; followed by toxic multinodular goiter in 102 (20.1%); solitary toxic nodule in 56 (11%); thyrotoxicosis without goiter in 44 (8.7%); subclinical hyperthyroidism in 22 (4.3.%); thyroiditis in 9 (1.8%); and thyrotoxicosis with solitary cold nodule in 4 (0.9%).