‘sticky’ endsoverlapping COMPLEMENTARY single strands at the termini of double-stranded DNA molecules that can stick the two ends of the molecule (or the ends of different molecules) together by COMPLEMENTARY BASE PAIRING. Cohesive ends are often generated by digesting DNA molecules with the same RESTRICTION ENZYME. Cohesive ends provide a means of sticking insert DNA to VECTOR in the construction of recombinant cloning vectors for GENE CLONING.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005