cofactor


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cofactor

 [ko´fak-ter]
an element or principle, e.g., a coenzyme, with which another must unite in order to function.
heparin cofactor II a member of the serpin group that inhibits thrombin.

co·fac·tor

(kō'fak'ter, tōr),
1. Synonym(s): coenzyme
2. An atom or molecule essential for the action of a large molecule, for example, heme in hemoglobin, magnesium in chlorophyll. Solo metal ions are regarded as cofactors for proteins, but not as coenzymes.

cofactor

/co·fac·tor/ (ko´fak-ter) an element or principle, e.g., a coenzyme, with which another must unite in order to function.
heparin cofactor II  a serine proteinase inhibitor of the serpin family that inhibits thrombin.

cofactor

(kō′făk′tər)
n.
1. One of two or more contributing factors.
2. A substance, such as a metallic ion or coenzyme, that must be associated with an enzyme for the enzyme to function.

co·fac·tor

(kō'fak'tŏr)
1. Synonym(s): coenzyme.
2. An atom or molecule essential for the action of a large molecule; e.g., heme in hemoglobin, magnesium in chlorophyll.

cofactor

a substance that is essential for the catalytic activity of some enzymes, binding to the enzyme only during the reaction. Cofactors can be metallic ions, or nonprotein organic molecules (coenzymes) such as vitamins in the B-COMPLEX.

co·fac·tor

(kō'fak'tŏr)
An atom or molecule essential for the action of a large molecule.

cofactor

an element or principle, e.g. a coenzyme, with which another must unite in order to function.
ristocetin cofactor
see ristocetin cofactor.
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References in periodicals archive ?
On the other hand binding energies of the products formed, when the FeMo cofactor reacted with the syngas constituents are low.
DFT analysis of metal complexes for selective nitrogen removal from the syngas based on binding energy criteria
This Km concept applies especially to cofactors that function as true substrates of the enzyme in question.
Metabolic correction: a functional biochemical mechanism against disease: Part 2: mechanisms and benefits
If h is a Darboux polynomial of system (1) with non-zero cofactor K then K = [k.
Darboux integrability of polynomial differential systems in [R.sup.3]
The anticoagulant mechanism of a crude fraction tested also suggests be dependent on cofactor heparin II to inhibit thrombin activity, but not on cofactors VIII and IX.
Anticoagulant properties of a crude sulfated polysaccharide from the red marine alga Halymenia floresia (Clemente) C. Agardh/Propriedades anticoagulantes de um polissacarideo sulfatado bruto da alga marinha vermelha Halymenia floresia (Clemente) C. Agardh
It is interesting that for each of the different modes of entry of C, H, N, O, P, and S, there is at least one cofactor present that enables their incorporation into components of the metabolome (unpubl.
Analysis of the intermediary metabolism of a reductive chemoautotroph
The Phase II clinical trial is a single arm, multicenter study to evaluate the safety and efficacy of treatment with CoFactor plus 5-FU in advanced breast cancer patients who have failed anthracycline and taxane chemotherapies.
ADVENTRX Begins Phase II Clinical Trial of Breast Cancer Treatment
In our series, HSV-2 DNA is not found integrated to human genome of adenocarcinoma of the uterine cervix, and does not seem to be a cofactor of HPV on the development of this cancer subtype," Dr.
HSV-2 is deemed not a cofactor in cervical cancer
Other possible regulatory factors include the presence of termination inhibitors or enhancers or a regulatory role of the magnesium cofactor.
Biotechnological development of domestic rubber producing crops
To determine whether to retain a cofactor in the backward elimination procedure, we used a threshold T such that Prob([F.
Mapping quantitative trait loci in plant breeding populations: use of parental haplotype sharing. (Crop Breeding, Genetics & Cytology)
There are three principle DNA methyltransferases, Dnmt 1, Dnmt 3a, and Dnmt 3b that catalyze the transfer of a methyl moiety from the cofactor S-adenosyl-L-methionine (SAM).
Retinoic Acid inhibition of Dnmt expression and activity in HL-60 cells
The investigators suggest several mechanisms that may explain genital herpes's role as a cofactor in HPV-induced cervical cancer.
Cervical cancer risk rises if women HPV also have herpes infection. (Digests)
The observed location of the GAP phosphate moiety is consistent with the flip-flop model for GAP binding, where the phosphate moiety of GAP initially bound at the "Pi" site flips to the "ps" site after hydride transfer during the cofactor exchange step.
STRUCTURAL ANALYSIS OF GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE FROM ESCHERICHIACOLI: DIRECT EVIDENCE FOR SUBSTRATE BINDING

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