codeine phosphate


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co·deine phos·phate

a water-soluble salt of codeine often used in the pharmaceutical preparation of liquid medications containing codeine.

codeine phosphate

an opioid analgesic and antitussive.
indications It is prescribed to suppress cough and to relieve mild to moderate pain.
contraindication Known hypersensitivity to opiates is the only contraindication.
adverse effects Among the more serious adverse reactions are depression of the central nervous system, paradoxic excitement, and drug dependence.

codeine phosphate

The phosphate of the alkaloid codeine; used because of its free solubility in water.
See also: codeine

codeine phosphate

narcotic opioid analgesic derived from morphine, used to control pain; also formulated with paracetamol (e.g. 30 mg codeine phosphate and 500 mg paracetamol tablets; Table 1); regular use predisposes to constipation; overdose suppresses both respiration and cough reflex, and can cause death
Table 1: Analgesic codeine preparations
AgentConstituents
Co-codamol(8/500) 8 mg codeine phosphate; 500 mg paracetamol
(15/500) 15 mg codeine phosphate; 500 mg paracetamol
(30/500) 30 mg codeine phosphate; 500 mg paracetamol
Co-dydramol(10/500) 10 mg dihydrocodeine tartrate; 500 mg paracetamol
Co-proxamol(32.5/325) 32.5 mg dextropropoxyphene hydrochloride; 325 mg paracetamol

Note: co-proxamol withdrawn in UK, due to adverse links to heart failure and respiratory depression

References in periodicals archive ?
You further admitted to having taken codeine phosphate on other occasions.
Pain following craniotomy: a preliminary study comparing PCA morphine with intramuscular codeine phosphate.
He then subsequently recorded in Patient A's medical records that he had administered 60mg of liquid Codeine Phosphate to Patient A.
4% of the area under the curve for codeine after controlled codeine phosphate administration (19).
For diarrhoea, there's loperamide and codeine phosphate, and for constipation, gentle laxatives.
Some tablets were seized, Codeine Phosphate and other tablets.
e probe was launched when medical bosses noticed an increase in the amount of codeine phosphate tablets being ordered by the Paediatric Intensive Care Unit, where Boynton worked.
The company said the JSP products are Butalbital, Aspirin, Caffeine with Codeine Phosphate Capsules USP, Digoxin Tablets USP and Levothyroxine Sodium Tablets USP.
Actavis, a United States generics drug manufacturer, has launched new formulations of Fioricet (butalbital, acetaminophen and caffeine capsules, USP) and Fioricet with Codeine (butalbital, acetaminophen, caffeine and codeine phosphate, USP), it was reported yesterday.
5 mg (generic version of Activella); oxcarbazepine tablets (generic version of Trileptal); meloxicam tablets (generic version of Mobic); Ascomp with codeine (generic version of Fiorinal with codeine); butalbital, acetaminophen, caffeine and codeine phosphate (generic version of Fioricet with codeine); cyclobenzaprine (generic version of Flexerfl); methylprednisolone (generic version of Medrol); polyethylene glycol powder (generic version of Miralax); folic acid tablets; and prednisone 1-mg tablets.