codeine


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codeine

 [ko´dēn]
an alkaloid obtained from opium or morphine, used as the base or as the phosphate or sulfate salt as an opioid analgesic, antitussive, and antidiarrheal.

co·deine

(kō'dēn),
Alkaloid obtained from opium, which contains 0.7-2.5%, but usually made from morphine. Used as an analgesic and antitussive; drug dependence (physical and psychic) may develop, but codeine is less liable to produce addiction than morphine; codeine is biotransformed to morphine, which accounts for most of codeine's effects.
Synonym(s): methylmorphine
[G. kōdeia, head, poppy head]

codeine

/co·deine/ (ko´dēn) a narcotic alkaloid obtained from opium or prepared from morphine by methylation and used as the base or as the phosphate or sulfate salt as an opioid analgesic, antitussive, and antidiarrheal.

codeine

(kō′dēn′, -dē-ĭn)
n.
An alkaloid narcotic, C18H21NO3, derived from opium or morphine and used as a cough suppressant, analgesic, and hypnotic.

codeine

Toxicology An oral opioid analgesic with antitussive activity Effects Blocks pain messages to brain; ↓ central response Used for Pain; antitussive. See Opioids.

codeine

An alkaloid derived from opium, used to control moderate pain, to relieve unnecessary coughing and to check diarrhoea. Codeine is not a drug of addiction and is available without prescription. The drug is on the WHO official list. It is contained in various branded preparations such as Co-Codamol, Codafen Continus, Galcodine, Kapake, Migraleve, Solpadol, Tylex and Zapain.

co·deine

(kō'dēn)
Alkaloid obtained from opium; analgesic and antitussive; drug dependence may develop, but codeine is more addictive than morphine.

codeine (kō´dēn),

n a crystalline alkaloid, morphine methyl ether that is used as an analgesic and antitussive. It is a controlled substance.
codeine sulfate/codeine phosphate,
n generic codeine;
drug class: narcotic analgesic, controlled substance schedule II, Canada N;
action: depresses pain impulse transmission in central nervous system by interacting with opioid receptors;
uses: mild-to-moderate pain, nonproductive cough.

codeine

an alkaloid obtained from opium or prepared from morphine by methylation; used as the phosphate or sulfate salt for analgesia and as an antitussive.
References in periodicals archive ?
In addition to limiting use in children following a comprehensive assessment of the risks and benefits of these products, labeling for adult-only use of prescription opioid cough and cold medicines that contain codeine or hydrocodone will also now include updated safety information.
In a few states, some codeine cough medicines are available OTC.
Addressing the press in Naivasha over the weekend, Mututho asked the KPPB to ban the importation of any drug-laced with codeine.
Almost all these syrups contain only 10mg of codeine and five per cent alcohol.
Hydrocodone, a hydrogenated ketone derivative of codeine, is metabolized by CYP2D6 to hydromorphone.
In April, the Food and Drug Administration issued a safety alert and warned against use of codeine and tramadol when breastfeeding.
10] It included sections covering demographics of respondents and treatment setting characteristics, experience with treating codeine patients, and general questions about treatment for individuals with codeine dependence, including new approaches or innovations.
We have searched the PubMed database until February 2015 using key words: Morphine, Codeine, and Opioid Metabolism
However, the fact that these step 3 agents may be more difficult to use and prescribe does not negate the fact that they are alternatives to codeine and tramadol, and are not subject to concerns about CYP2D6 genotype.
Two empty boxes of codeine phosphate - an opiate painkiller - were later found in the bin.
In the study, researchers reviewed data on 28,100 patients newly treated with tramadol and 305,924 treated with the pain reliever codeine between 1998 and 2012.