cochlear hair cell

cochlear hair cell

n.
A sensory cell in the spiral organ in synaptic contact with sensory as well as efferent fibers of the auditory nerve. Also called Corti's cell.
References in periodicals archive ?
Caption: TPF imaging of the Cochlear hair cell sample stained with PI in a) a wide image of the sample, b) zoomed region of interest (yellow square) and c) the same area as (b) after selectively ablating a cell marked in the white circle.
Hearing losscanoccurasa result of a local inflammatory response leading to cochlear hair cell death or as a result of a direct cytopathic effect of the virus in the inner ear.
Effect of low-level laser therapy on cochlear hair cell recovery after gentamicin-induced ototoxicity.
The mechanism of loudness recruitment is not yet clear, but it is common in general sensorineural deafness and considered an indication of cochlear hair cell diseases.8 All AN patients did not show loudness recruitment, indicating that the auditory nerve transmission pathway of AN was affected.
Zhang et al., "Cotransfection of Pax2 and Math1 promote in situ cochlear hair cell regeneration after neomycin insult," Scientific Reports, vol.
Myo3b localizes at cochlear hair cell stereocilium tips, similar with the localization of Espin1 and Myo3a [37].
Hosoya et al., "Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma," Neuron, vol.
Lack of function within the cochlear hair cells leads to development of deafness.12 Similarly, CDH23, (OMIM: 605516) gene encoding Cadherin-23 showed mutation in both NSHL (DFNB12) and Usher syndrome type ID (USH1D).13 CDH23 contain 69 exons and codes 3,354-amino-acid protein comprising 27 cadherin extracellular (EC) repeats, a transmembrane domain and a unique cytoplasmic domain.
The cochlear hair cells are the only disrupted sites resulting from Tric KO as reported previously [10], despite the fact that the ES and scala media in the cochlea share a single endolymphatic space.
The cochlear hair cells are divided into two types: outer hair cells (OHCs) and inner hair cells (IHCs).
[9,26] Thyroid hormone is suggested as a first transcriptional regulator of the motor protein prestin and as a direct or indirect modulator of subcellular prestin distribution [27] and autonomous functioning of TR[alpha] and TR[beta] in cochlear hair cells modulates active cochlear mechanics and inner hair cell output activity.
Acoustic information carried by sound waves is transduced into electric signals by cochlear hair cells (HCs) and transmitted to spiral ganglion neurons (SGNs) and central auditory nuclei.