cocaine cardiotoxicityA generic term for the direct and indirect effects of cocaine on the heart.
Chest pain, tachycardia, hypertension, acute myocardial infarction (MI), ventricular arrhythmia, asystole, congestive heart failure, sudden death due to cardiovascular collapse.
• Arrhythmias Conduction defects
• Acute MI Coronary arterial spasm; intimal hyperplasia.
• Catecholamine effects Contraction band necrosis, myocardial fibrosis, and arrhythmias.
Vasoconstriction and direct cardiac toxicity.
Cocaine, acute effects
Contraction bands and necrosis.
Cocaine, chronic effects
• LV hypertrophy
• Fibrosis—patchy and irregular
• Intramyocardial arterial medial thickening.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
cocaine cardiotoxicityA condition caused by long-term cocaine use Clinical Chest pain, tachycardia, HTN, acute MI, ventricular arrhythmia, asystole, CHF, sudden death due to cardiovascular collapse. See Cocaine.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.