Vitamin B12 (Cobalamin
, Cyanocobalamin) Major Applications/End users: Hospitals, Clinics & Others
Odds ratio with 95% confidence intervals were calculated to see if cobalamin
deficient women were more likely to develop GDM.
Current concepts in the diagnosis of cobalamin
 Nonstandard abbreviations: MMA, methylmalonic acid; ALT, alanine transaminase; AST, aspartate transaminase; RDW, red cell distribution width; HCT, hematocrit; EMG, electromyography; Cbl, cobalamin
; Met, methionine; Hcy, homocysteine; AdoCbl, adenosylcobalamin; MeCbl, methylcobalamin; tHcy, total Hcy; 2MCA, 2-methylcitric acid; SCD, subacute combined degeneration of spinal cord; PA, pernicious anemia; [N.sub.2]O, nitrous oxide; GDS, Global Drug Survey; SAM, 5- adenosykmethionine; Hb, hemoglobin.
The aim of this study is to develop an in vitro model capable of mimicking low grade gastric inflammation and to use this model to investigate the activity of clinically relevant levels of cobalamin
as defined by earlier studies and finally to enhance our current understanding between the impact of active and inactive cobalamin
in the developed gastric model of inflammation.
We have noticed relevant lower cobalamin
levels in mothers from CHD and non-CHD group compared to their children.
is vital for DNA synthesis and hematopoietic cell division.
(17) This same group of investigators has also described pseudo-TTP in 2 patients with food- cobalamin
Pezacka, "Identification and characterization of two enzymes involved in the intracellular metabolism of cobalamin
. Cyanocobalamin [beta]-ligand transferase and microsomal cob(III) alamin reductase," Biochimica et Biophysica Acta (BBA)--General Subjects, vol.
An earlier study looked at the combined effect of cobalamin
with ascorbic acid on three ascites tumor cell types and found a synergistic effect decreasing mitotic counts and survival of tumor cells.
Megaloblastic anaemias are disorders resulting from abnormal maturation of haematopoietic stem cells due to inhibition of DNA synthesis, and two vitamins namely, Cobalamin
(Vitamin B12) and Folic acid are essential for DNA biosynthesis.
status is determined by the cobalamin
content in the breastmilk and the maternal cobalamin
concentration during lactation.