A common genetic polymorphism (46 C to T substitution) in the 5'-untranslated region of the coagulation factor XII gene is associated with low transition efficiency and decrease in plasma FXII level.
A common C-T polymorphism at nt 46 in the promoter region of coagulation factor XII is associated with decreased factor XII activity.
Coagulation factor XII activity, activated factor XII, distribution of factor XII C46T gene polymorphism and coronary risk.