Acquired coagulation factor V (FV) inhibitors are rare and their presentations varied.
Isolation and study of an acquired inhibitor of human coagulation factor V. J Clin Invest.
Mutation in blood coagulation factor V
associated with resistance to actuated protein C.
Joseph Miletich provided an excellent overview of what mutations in the coagulation factor genes mean in the overall scheme of risk for thromboembolic disease with advancing age and with the presence of heterozygosity for the coagulation factor V
Leiden gene mutation.