coagulase

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Related to coagulase test: Indole test, Oxidase test, Catalase test

coagulase

 [ko-ag´u-lās]
a bacterial enzyme that reacts with a cofactor found in blood plasma to catalyze the formation of fibrin from fibrinogen. It is produced by most of the virulent strains of staphylococci, and by Yersinia pestis.

coagulase

/co·ag·u·lase/ (-lās) an antigenic substance of bacterial origin, produced by staphylococci, which may be causally related to thrombus formation.

coagulase

(kō-ăg′yə-lās′, -lāz′)
n.
Any of various enzymes, such as rennin or thrombin, that induce coagulation.

coagulase

[kō·ag′yəlās]
Etymology: L, coagulare, to curdle
an enzyme produced by bacteria, particularly Staphylococcus aureus, that promotes the formation of fibrin from fibrinogen to form thrombi.

coagulase

An enzyme secreted by the micro-organism Staphylococcus aureus that causes clotting in blood plasma by converting prothrombin to thrombin. This ability probably contributes to the tendency of the organism to form abscesses.

coagulase

an antigenic substance of bacterial origin, produced chiefly by staphylococci, which may be causally related to thrombus formation.

coagulase test
enzymatic conversion of fibrinogen in rabbit plasma to fibrin is used as a means of identifying pathogenic species of staphylococci. The test may be carried out rapidly on a slide or in several hours or overnight in a tube. Most coagulase-positive staphyloccoci are pathogenic; coagulase-negative ones commonly are not.
References in periodicals archive ?
aureus isolates on the basis of coagulase test were also characterized by PCR and found to be positive 32 (82.
Then followed by the specific biochemical test for Staphylococcus aureus such as catalase and coagulase tests were carried out.
Rapid identification of Staphylococcus aureus in blood cultures by use of the direct tube coagulase test.
aureus isolates differed in toxigenic potential based on coagulase test (HP, SP and SP+HP) and DNase test.
Isolates were identified by colony morphology, catalase and coagulase test.
aureus colonies were confirmed with a latex agglutination test (Staphaurex Plus; Murex Diagnostics Ltd, Dartford, UK), a tube coagulase test with rabbit plasma, and DNase (DNase agar; Oxoid Ltd, Basingstoke, UK).
If a coagulase test is positive, the organism is identified as S.
The staphylococci strains were subjected to slide and tube coagulase test and those strains which were negative by both methods were identified as Coagulase Negative Staphylococci (CONS).
Staphylococcal isolates were subjected to coagulase test to differentiate Staphylococcus aureus from other Staphylococcal species.