All the cardioprotective changes are reverted back resulting in respiratory acidosis, increased plasma ionic calcium thus augmenting the coagulability
of blood with a vulnerability for thrombosis, i.e., intravascular clotting.
Researchers at Tokyo Medical and Dental University have shown that an analyzer recently developed to measure blood coagulability
has the sensitivity to detect hypercoagulatibility associated with stroke risk in those without atrial fibrillation (AF), a common risk factor for stroke.
On review of the history, patient stressed on the mode of onset of the symptoms which was acute in nature, but denied any previous history of venous thrombosis or any drug intake which increases blood coagulability
. There was no history of prolonged immobilization or any cardiac procedure or central venous cannulation.
Physiological factors that predispose to thrombosis are-changes in blood flow like stasis or hyperviscosity of blood as in dehydration, Congestive Heart Failure, Polycythaemia and changes in coagulability
Cardiovascular mortality takes place when the body exceeds the thermoregulatory threshold generating changes in heart rate, viscosity of the blood, change in coagulability
of the blood, reduction in cerebral perfusion and attenuation in vasomotor responses (38).
Stasis, alteration of coagulability
of the blood and vessel wall damage increases the risk of thrombus formation.
Study results have also shown that recent exercise can cause changes in TEG variables, including postexercise normalization of certain TEG parameters in dogs with hemophilia A and decreased coagulability
in race horses.
Table 1: Abnormal Laboratory Results in MSCIS [up arrow] Inflammatory markers (IL-1, IL-6, CRP, Ferritin, TNF-[alpha] [down arrow] Platelets [up arrow] Liver Function Tests [up arrow] Coagulability
Insulin Resistance Abnormal Lipid Panel Abnormal Alkaline Phosphatase Normal/Abnormal Thyroid function [down arrow] Salivary DHEA [down arrow] [up arrow] Salivary Cortisol [down arrow] Salivary Progesterone [down arrow] Testosterone Table 2: Antimicrobial Effects of Cistplatin Gram positive: E.
It is strongly believed that abnormal coagulability
state may be reverted by effective use of anti-snake venom25.
In normal controls, both age and gender affect coagulability
as measured by thrombelastography.
Increased cholesterol is associated with increased coagulability
and increased platelet count .
Ultrafine inhaled particles accumulated in the lungs are capable of translocating from the airways into the bloodstream (23) causing systemic inflammation via oxidative stress that mediates endothelial dysfunction and atherosclerosis (44) and increases blood coagulability
by activating platelets and coagulation factors such as fibrinogen.