Given the above, the objective of this study was to microencapsulate Lactobacillus acidophilus La-5 using complex coacervation
followed by freeze-drying, then characterize the particles and evaluate the viability and stability of the encapsulated culture during storage.
Recent scientific studies have shown the importance and the effect of microencapsulation by complex coacervation
on the controlled availability of propolis extract (NORI et al., 2011) and oral drug celecoxib (CHENG et al., 2010).
Micro particles obtained by complex coacervation
: influence of the type of reticulation and the drying process on the release of the core material.
Sawicka, "Microencapsulation of cholecalciferol by coacervation
," Die Pharmazie, vol.
Razavi et al., "Complex coacervation
of [beta]-lactoglobulin--K-carrageenan aqueous mixtures as affected by polysaccharide sonication," Food Chemistry, vol.
Dima, "Microencapsulation of essential oil of pimento [Pimenta dioica (L) Merr.] by chitosan/k-carrageenan complex coacervation
method," Innovative Food Science & Emerging Technologies, vol.
Chemical methods tend to be preferred for non-solid core materials and include coacervation
and sol-gel approaches.
Several techniques for manufacturing microspheres have been developed, such as electrospray drying [14, 15], solvent evaporation [16-18], emulsion crosslinking [19, 20], ionic gelation technique , direct dispersion method , microfluidic channels , supercritical carbon dioxide , coacervation
method , and free radical emulsion polymerization .
method was used to produce omega-3 nanocapsules.
Techniques including spray drying, melt extrusion, coacervation
, and aqueous emulsions have been used to generate fragrance-containing microparticles.
Design of nimesulide-chitosan microparticles by pH change coacervation
Trotta, "Formulation of curcumin-loaded solid lipid nanoparticles produced by fatty acids coacervation
technique," Journal of Microencapsulation, vol.