cloxacillin


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Related to cloxacillin: Cloxacillin Sodium

cloxacillin

 [kloks″ah-sil´in]
a semisynthetic penicillin; its sodium salt is used in treating staphylococcal infections due to penicillinase-positive organisms.

cloxacillin

(klŏk′sə-sĭl′ĭn)
n.
A semisynthetic penicillin, C19H18ClN3O5S, that is resistant to penicillinase, used in the form of its sodium salt primarily to treat infections caused by penicillinase-producing staphylococcus bacteria.

cloxacillin

Infectious disease A beta-lactam penicillin that is not hydrolyzed by staphylococcal penicillinases, ie most isolates of S aureus and some coagulase-negative staphylococci are susceptible to cloxacillin; it is also useful for streptococci

cloxacillin

A semisynthetic penicillin antibiotic that resists the destructive penicillinase enzymes that some staphylococci produce. The drug also resists degradation by stomach acid and so can be taken by mouth. The drug is on the WHO official list. A brand name of a preparation combined with ampicillin is Ampiclox.
References in periodicals archive ?
Isolates were resistant to Cloxacillin, Ampicillin, Cefazolin and Cotrimoxazole.
The percentage yield and some physical properties of the iron (III) complexes of ciprofloxacin (CPF-[Fe.sup.3+]), cloxacillin (Clox-[Fe.sup.3+]), and amoxicillin (Amox-[Fe.sup.3+])are giveninTables 1 and 2.
These results suggest that there were differences in the percentage of isolates that showed resistance to cloxacillin between NORM and HIGH use farms.
The agency's tests of the product found that it contained cloxacillin, which is a member of the same class of antibiotics as penicillin.
For BORSA-associated infections, [beta]-lactam antimicrobial drugs, including high-dose penicillinase-resistant penicillins (PRPs) (e.g., cloxacillin) or [beta]-lactam/[beta]-lactamase--inhibitor combinations (e.g., ampicillin/sulbactam) are regarded as treatments of choice (4,6,9).
He was febrile on admission and was empirically treated with intravenous penicillin and cloxacillin for cellulitis.
Isoelectric focusing (IEF) to determine isoelectric points (pIs) and general inhibitor characteristics with an ampholine polyacrylamide gel (pH range 3.5-9.5) on a flatbed apparatus (Multiphor LKB, Bromma, Stockholm, Sweden) indicated that this organism produced a [beta]-lactamase enzyme with a pI of 6.9 that was inhibited by clavulanic acid and not by cloxacillin (8,9).
pseudodiphtheriticum infection was diagnosed, treatment with intravenous cloxacillin (1 g 3 times/day) and amoxicillin plus clavulanic acid (1 g 3 times/day) was started.