clotrimazole


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clotrimazole

 [klo-trim´ah-zōl]
a synthetic broad-spectrum antifungal agent applied topically to the skin in the treatment of candidiasis and various forms of tinea, and administered intravaginally in the treatment of vulvovaginal candidiasis and orally in the prevention and treatment of candidiasis of the mouth and throat.

clotrimazole

(klō-trĭm′ə-zōl′)
n.
A broad-spectrum antifungal drug, C22H17ClN2, used topically to treat a variety of superficial fungal infections, including candidiasis and ringworm.

clotrimazole

Infectious disease An antifungal imidazole used topically for candidiasis Adverse effects Nausea, dizziness, diarrhea, changed LFTs

clotrimazole

A drug effective against a wide range of fungi. It is used in the form of creams, for local application. Brand names are Canesten and Masnoderm. Formulated with BETAMETHASONE it is marketed under the brand name Lotriderm.

antifungal agent 

Any substance which destroys or prevents the growth of fungi. It is one of the antibiotic groups. There are several classes of antifungal drugs: Polyenes, which cause an increase in fungal cell wall permeability leading to its death. Examples: amphotericin B, natamycin, nystatin. Azoles, which act either by inhibiting the synthesis of ergosterol, a component of fungal cell wall or by causing direct wall damage. Examples: clotrimazole, econazole, fluconazole, itraconazole, ketoconazole, miconazole. Pyrimidines, which interfere with the normal function of fungal cells. Example: flucytosine. Syn antimycotic agent.
References in periodicals archive ?
More than 83% of the patients were free of symptoms 1 week after treatment in previous studies using single-dose clotrimazole 500 Mg.[5,9] With the lower mycologic cure rate in the present trial, one would also expect a lower symptomatic cure rate.
Topical 2% clotrimazole cream and 2% fusidic acid cream showed greater reduction in colour, intensity and Wood's lamp reflection score in erythrasma during the first week.
Invasive treatment of canine nasal aspergillosis with topical clotrimazole. Vet.
of Cure % Improved Agents Cases Rate Treated Clotrimazole 60 66.7% 16.60% Miconazole 25 56% 20% Silver 15 40% 20% sulphadiazine Antifungal % No % No Impression Agents Response Follow up Clotrimazole 8.30% 8.30% Markedly Effective Miconazole 12% 12% Moderately Effective Silver 13.32% 26.64% Moderately sulphadiazine Effective Fig.
Commonest organism isolated is Aspergillus Niger and responded well to topical clotrimazole.
Taro competes with clotrimazole, among other feminine care products.
Among 110 patients that were fulfilling the criteria 55 were treated with 2% sertaconazole cream and 55 with 1% clotrimazole cream.
After cleaning the fungal and epithelial debris from the ear canal, topical antifungal agents--1% Clotrimazole was used in the form of ear drops.
Recently, another supplier joined the generic clotrimazole market when Clay-Park Labs Inc.
The announcement comes on the heels of Food and Drug Administration approval for Taro's clotrimazole topical, a generic version of Schering-Plough Corp.'s Lotrimin.
The FDA says the history of safe use of Gyne-Lotrimin's active ingredient, clotrimazole, convinced the federal agency that the drug can be sold without a prescription.
Tender notice number : Tendor no.E551 Clotrimazole vaginal PessariesID:2018_HBPCL_304072_1