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gangrene occurring in a wound infected with various anaerobic spore-forming bacteria, especially Clostridium perfringens and C. novyi, which cause rapidly advancing crepitation of the surrounding tissues, due to gas liberated by bacterial fermentation, and constitutional toxic and septic symptoms including cytotoxic damage to kidney, liver, and other organs.
Synonym(s): clostridial myonecrosis, emphysematous gangrene, gangrenous emphysema, progressive emphysematous necrosis
Farlex Partner Medical Dictionary © Farlex 2012
clostridial myonecrosisGas gangrene, necrotizing subcutaneous infection Emergency medicine A rapidly progressive, life-threatening form of gangrene that is a rare complication of 'dirty' traumatic wounds, which are infected with Clostridium spp Etiology War wounds, bee stings, venipuncture; CM is due to production of toxins, especially alpha toxin, leading to tissue necrosis, shock Management Surgical decompression, excision of necrotic tissue, penicillin, hyperbaric oxygen. See Hyperbaric oxygen therapy, Necrotizing fasciitis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.