Patients in the observation group were given 600 mg of clopidogrel
bisulfate tablets immediately after admission (national approval number: J20130083; Sanofi-Aventis (Hangzhou) Pharmaceutical Co., Ltd., China; specification: 75 mg/tablet; batch number: 3A579, 4A757, 5A458) and 300 mg of aspirin enteric-coated tablets.
Ticlopidine and clopidogrel
block platelet activation by ADP and are considered to be marginally more effective than aspirin.
is the only P2Y12 inhibitor available as a generic medication in the United States.
Ticagrelor versus clopidogrel
in patients with acute coronary syndromes.
When stenting is used to prevent a heart attack, aspirin plus clopidogrel
is the gold standard.
The researchers found that major ischemic events occurred in 5.0 and 6.5 percent of patients receiving clopidogrel
plus aspirin versus aspirin plus placebo, respectively (hazard ratio, 0.75); most events occurred during the first week after the initial event.
As the use of clopidogrel
has proliferated, hypersensitivity reactions have been increasingly recognized .
On discharge, the patient was started on multiple new medications including clopidogrel
SLNs containing clopidogrel
were prepared by the high shear hot homogenization and ultrasound method following a standard procedure .
Entre esos agentes se encuentra el clopidogrel
, el cual es un derivado estructural de la ticlopidina y tambien es un pro-farmaco.
However, some patients may suffer from attenuated platelets inhibition to clopidogrel
high on treatment platelets reactivity (HTPR) which hinders achieving the optimum outcome of DAPT.
Unfortunately, a significant minority of patients ([greater than or equal to] 35%) do not respond adequately to clopidogrel
[16-25]; and a similar but lesser problem exists for aspirin [16, 18, 20, 26, 27].