Oral mucositis is characterized by atrophy and rupture of epithelial tissue, followed by ulcerations with direct clonogenic cell
death as a consequence of oxidative stress arising from chemotherapeutic and radiotherapeutic treatments of patients with head and neck cancer.
Relationships between clonogenic cell
survival, DNA damage and chromosomal radiosensitivity in nine human cervix carcinoma cell lines.
Meyn, "Clonogenic cell
survival assay," Methods in Molecular Medicine, vol.
survival assay was used in our study to determine antiproliferative effects of AA extracts by checking its ability to inhibit cancer cells from dividing and forming colonies.
In order to obtain optimal tumor cell killing with uniform clonogenic cell
density and to avoid necrosis of the normal cell present within the target volume, the dose distribution within the target volume should be uniform .
An analytical expression for TCP, based on a binomial expression with the assumption that every clonogenic cell
has to be eradicated in order to control the tumor, that takes into account the heterogeneity in dose at cellular level was presented in a previous paper .
Tissue-specific damage such as mucositis, dermatitis, or fibrosis is no longer thought to be the sole consequence of direct clonogenic cell
Aldehyde dehydrogenase activity is significantly higher in the clonogenic cell
population than it is in nonstem tumor cells.
In the present study, we isolated and purified rabbit BMSCs based on their ability to form adherent clonogenic cell
1) on lung cancer cells proliferation, clonogenic cell
growth and expression of lung cancer markers and cancer-related genes.
The Bowman-Birk protease inhibitor enhances clonogenic cell
survival of ionizing radiation-treated nucleotide excision repair-competent cells but not of xeroderma pigmentosum cells.
The validity of the LTC-IC assay is dependent on the existence of a linear relationship between the endpoint measured (clonogenic cell
output as assessed after 5 weeks of culture) and the number of LTC-IC in the original test suspension down to limiting numbers of LTC-IC.