clonogenic assay


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clo·no·gen·ic as·say

in vitro culturing of neoplastic cells to test their radiosensitivity or chemosensitivity, and to measure probable clinical efficacy of a therapeutic agent.
References in periodicals archive ?
Furthermore, histopathological analysis and hematopoietic progenitor clonogenic assay of tissues collected show a significant increase in bone marrow cell numbers and improved regenerative capability into all blood lineages.
Positive Data From Tests Of ARS Treatment Presented: PLX-R18 Demonstrated Significant Increase In Survival Rates, Recovery
We further determined the roles of Grail in tumorigenesis by clonogenic assay in KB/Grail and KB/shGrail cells.
Grail suppresses stress-induced apoptosis and colony formation in oral cancer cells
Cell lines with amplified DSCC1 locus are dramatically affected in clonogenic assay by DSCC1 silencing, while cell lines without DSCC1 amplification maintain normal clonogenic ability after DSCC1 silencing.
Effect of Upregulated DNA Replication and Sister Chromatid Cohesion 1 Expression on Proliferation and Prognosis in Hepatocellular Carcinoma
For the clonogenic assay, 1 x [10.sup.3] cells were plated in 60-mm dishes and cultured in medium containing DMSO or oridonin for 2 to 3 weeks.
Oridonin induces growth inhibition and apoptosis in human gastric carcinoma cells by enhancement of p53 expression and function
To confirm the capacity of selected proinflammatory cytokines to drive the HSPCs toward a myeloid lineage, we performed clonogenic assay.
Mobilized Peripheral Blood versus Cord Blood: Insight into the Distinct Role of Proinflammatory Cytokines on Survival, Clonogenic Ability, and Migration of [CD34.sup.+] Cells
The values of SER10 were calculated from the curves of clonogenic assay. The enhanced in vitro and in vivo radiosensitization effect and possible underlying mechanism were reported for the first time, which solidified the promising application of curcumin loaded PVP-PCL nanoparticles as a novel radiosensitizer.
Enhanced Radiosensitization Effect of Curcumin Delivered by PVP-PCL Nanoparticle in Lung Cancer
Results of clonogenic assay (CFU) and flow cytometry analyses (FACS) of mesenchymal stem cells (MSCs, (b)), endothelial progenitor cells (EPCs, (c), (d)), and hematopoietic stem cells (HSCs, (e), (f)).
Combined Analysis of Endothelial, Hematopoietic, and Mesenchymal Stem Cell Compartments Shows Simultaneous but Independent Effects of Age and Heart Disease
To determine the long-term cytotoxicity effects of apigenin, a clonogenic assay was used [51].
Oxidative Stress Triggered by Apigenin Induces Apoptosis in a Comprehensive Panel of Human Cervical Cancer-Derived Cell Lines
Clonogenic Assay. A clonogenic assay was performed to determine the effects of STS treatment on the survival and division of the radiation-treated H9c2 cells.
Sodium Tanshinone IIA Sulfonate Prevents Radiation-Induced Toxicity in H9c2 Cardiomyocytes
Clonogenic Assay. Cells were plated in 60 mm dishes (1000/dish) and were treated with different concentrations of wogonin or MPP for 48 hours.
Therapy Effects of Wogonin on Ovarian Cancer Cells
The clonogenic assay determines the ability of a cell to proliferate indefinitely, thereby retaining its reproductive ability to form a large colony or a clone.
Apoptotic effect of eugenol envolves G2/M phase abrogation accompanied by mitochondrial damage and clastogenic effect on cancer cell in vitro
Clonogenic assay. For the clonogenic assay, HEK293T cells were seeded into six-well dishes at 500 cells/well and incubated overnight in complete medium.
E2F1-mediated FOS induction in arsenic trioxide-induced cellular transformation: effects of global H3K9 hypoacetylation and promoter-specific hyperacetylation in vitro
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