The Kruskal-Wallis test showed that the onset of PTZ-induced clonic
seizure was different between treatment groups (X (2)(8)=45.85, P<0.001).
The patient had clonic
jerks in the left arm that were time-locked with sharp waves.
Other generalized seizure types may also occur, including absence seizures and generalized tonic clonic
Treatment Onset of clonic
action in s Onset of tonic action in s (dose, Mean [+ or -] SEM Mean [+ or -] SEM mg/kg, i.p.) PTZ Control 47.80 [+ or -] 1.69 72.60 [+ or -] 1.78 (85) Embelin (2.5) 66.60 [+ or -] 1.40 (a) 88.60 [+ or -] 1.17 (a) Embelin (5) 88.20 [+ or -] 0.92 (a) 143.40 [+ or -] 1.40 (a) Embelin (10) 230.00 [+ or -] 4.44 (a) 349.40 [+ or -] 3.37 (a) Diazepam (4) Absence of convulsions Absence of convulsions Treatment No.
Phenytoin (PHT) is indicated for the treatment of partial and both primary and secondarily generalized tonic clonic
The aqueous extract at doses of 800, 1600, and 3200 mg/kg significantly increased the latency time to the onset of myoclonic seizure by 221.2, 370.6, and 378.5% ([F.sub.(5,41)], 40.8; P < 0.001) and clonic
seizure by 310, 394.6, and 401.9% ([F.sub.(5,41)], 36.9; P < 0.001) in comparison to the control group (figure 1).
The suppression of clonic
seizure was taken as an indicator of anticonvulsant action.
For instance, if only a portion of the primary motor cortex is affected by epileptic activity, the patient may experience clonic
jerking confined to the contralateral arm, while memory and awareness remain intact.
status epilepticus which may be accompanied by apnea is the most prominent seizure type.
Here, we describe a patient who developed tonic clonic
seizures due to Theophylline toxicity, having ceased smoking 2 weeks earlier.
This event is characterized by a loss of consciousness, a brief period of muscle rigidity (tonic phase) followed by rhythmic jerking of all the patient's extremities (clonic
phase) (Yamamoto et al., 2004).
A day before admission she had generalized tonic clonic
convulsions that progressed to status epilepticus, followed by loss of consciousness.