In all 18 patients included in this study, we were able to prove that samples originating from the same patient were
clonally identical and at the same time
clonally distinct from samples originating from other patients when using this NGS method.
This is likely due to the spread of
clonally related CRAB isolates, which were responsible for nosocomial infections between May and August 2014.
Fuzi, "Nationwide spread of
clonally related CTX-M-15-producing multidrug-resistant Klebsiella pneumoniae strains in Hungary," European Journal of Clinical Microbiology & Infectious Diseases, vol.
VHL-null 786-O cells were transfected and
clonally selected for stable expression of either WT or Y175C VHL or GFP (null), as indicated.
This
clonally expanded population of [CD4.sup.+] CTLs, detected in both peripheral blood and fibrotic lesions of IgG4-RD patients, seems to actively contribute to the disease process, particularly to tissue injury and fibrosis.
NKT cells play critical roles in the induction of oral tolerance by inducing regulatory T cells producing IL-10 and transforming growth factor beta, and by
clonally deleting antigen-specific T cells.
Such
clonally related fields can be much larger than the actual carcinoma.
This is followed by proliferation of non-clonal fibroblasts and abnormal shedding of growth factors from
clonally expanded megakaryocytes which induces hyperactivity.
Chequerboard (CB) method: Activity of TGC and CL combination, and combinations of these antibiotics individually with AK, CIP, MR, MXF, RF against
clonally unrelated 15 MDR A.
Stone and his coinvestigators recently identified these CD4+ cytotoxic T cells as a novel population of
clonally expanded T cells with SLAMF7 as a surface marker.
In general, mutation assays measure both unique and
clonally expanded mutations; however, the relative contribution of mosaicism to the overall mutation burden is rarely considered in these assays.
Therefore, pulmonary vascular and airway smooth muscle cells, proximal endothelium, and pericyte-like cells derive
clonally from these progenitors.