In summary, serotype 7C remains a rare cause of IPD in England and Wales but is linked to a sudden, rapid increase in cases of IPD because of clonal expansion
of ST177, previously associated with vaccine serotype 19F.
* Second phase (clonal expansion
): Additional genetic alterations develop and the patch proliferates taking advantage of its enhanced growth potential and forms a field which displaces the normal epithelium.
of Mutations and the Induction of Mosaicism
Effect of lignosulfonic acid on mitotic clonal expansion
As briefly mentioned in the Introduction, oncogene suppression under severe energy restriction most likely mirrors the fact that this condition is incompatible with sustained oncogenic signalling which drives commitment to clonal expansion
Plasma cell dyscrasias include a variant of proliferative disease, characterized by clonal expansion
of plasma cells in the bone marrow or other tissues, producing a massive quantity of monoclonal immunoglobulin called paraprotein or Mprotein .
The larger this diversity, the better the likelihood of a pathogen being effectively bound by a B or T cell, allowing for subsequent clonal expansion
and a targeted immune response.
Citation: Filippo Calzolari et al.; "Fast clonal expansion
and limited neural stem cell self-renewal in die adult subependymal zone"; Nature Neuroscience, 2015; DOI: 10.1038/nn.3963
The potential benefit of the HLC quantification method is to provide an accurate quantification for IgA clonal expansion
by measuring total IgA[kappa], total IgA[lambda], and IgA[kappa]/IgA[lambda] ratios (9).
of the myeloid blasts and the loss of normal hematopoiesis are the main characteristic of acute myeloid leukemia.
The discovery that HIV can cause clonal expansion
could also have implications for gene therapy, says Angela Ciuffi, a virologist at the University of Lausanne in Switzerland.
Coagulin-L inhibited mitotic clonal expansion
(MCE) by delayed entry in G1 to S phase transition and S-phase arrest.