clofibrate


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clofibrate

 [klo-fi´brāt]
an agent used to reduce elevated serum lipids in treatment of hyperlipoproteinemia, administered orally.

Clofibrate (Altromed-S)

Medication used to lower levels of blood cholesterol and triglycerides.
References in periodicals archive ?
The number who had actually died from heart attacks was equal in both groups plus considerably more who had been treated with clofibrate had died from other diseases.
SW480 cells were treated with PPAR[alpha] agonist (clofibrate); the results showed that clofibrate significantly increased autophagosome accumulation (Figure 5(a)).
Campbell et al., "Evaluation of the carcinogenic potential of clofibrate in the FVB/Tg.AC mouse after oral administration--Part I," International Journal of Toxicology, vol.
Schaaf, "Comparison of clofibrate and chlorpropamide in vasopressin-responsive diabetes insipidus," Metabolism: Clinical and Experimental, vol.
There are four classes of lipid-lowering drugs in the market: the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (the "statins"), the fibrates (gemfibrozil, clofibrate, and fenofibrate), niacin/nicotinic acid, and the bile acid binding resins (colestipol and cholestyramine).
On the other hand, Lopid (gemfibrozil) and Atromid (clofibrate) are reported to cause sleepiness.
Because some peroxisome proliferator activated-receptor alpha (PPAR[alpha]) activators are known to induce hepatocarcinogenesis in rodent liver, we investigated whether PPAR[alpha] activators (e.g., benziodarone, benzbromarone, fenofibrate, clofibrate, ibuprofen, WY-14643, gemfibrozil) were randomly distributed across modules in RLV, PHH, and PRH.
Fibrate medications include gemfibrozil (Lopid), fenofibrate (TriCor) and clofibrate (Atromid-S).
Linnainmaa, "Induction of sister chromatid exchanges by the peroxisome proliferators 2,4-D, MCPA, and clofibrate in vivo and in vitro," Carcinogenesis, vol.
Peroxisome proliferation was first reported in rats treated with clofibrate in the 1960s [9].