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an agent used to reduce elevated serum lipids in treatment of hyperlipoproteinemia, administered orally.
clofibrate/clo·fi·brate/ (-fi´brāt) an antihyperlipidemic used to reduce serum lipids.
indications It is prescribed in the treatment of high blood levels of triglycerides occurring alone or in combination with high cholesterol levels.
contraindications Liver or kidney dysfunction, pregnancy, lactation, biliary cirrhosis, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse reactions are nausea, diarrhea, weight gain, and a syndrome resembling influenza. This drug interacts with many other drugs and should not be used together with the HMG-CoA reductase inhibitors (statins) used to lower plasma cholesterol levels because this combination has an increased risk for myositis and rhabdomyolysis.
Medication used to lower levels of blood cholesterol and triglycerides.
Mentioned in: Thyroid Function Tests
an antihyperlipidemic drug.