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Ostac®, Bonefos® Metabolism A biphosphonate used to manage osteoporosis, Paget's disease of bone, cancer-induced hypercalcemia in Pts with prostate CA, myeloma and other CAs by regulating osteoclastic activity Therapeutic effect ↓ pain, risk of Fx, new bone metastases. See Osteoporosis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Patient discussion about clodronate

Q. why is it bad to walk outside with wet hair after you have taken a shower , when it's clod out side? what can happen to me if i will do it ?

A. I've done this several times. The few times, my mother told me not to, I caught a cold.

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References in periodicals archive ?
Our main products are modern pure-Chinese medicine preparation Kailing series (injection, capsules, oral solution, granules), matrine injection, compound diclofenac sodium chlorphenamine maleate tablets being a good remedy for a cold (Ganmaotong), YadanziYouruinjection&oral emulsion, vincristine sulfate (freeze-dry powder injector) for injection, asparaginase (freeze-drying) for injection, cancer chemotherapeutic Dewei (clodronate disodium) injection&capsules, nitroglycerin injection, Xiaozhiling tables, Xinmaining tablets, Duomiteding (fleroxacin) tablets, bicarbonate hemodialysis agent (MingxingNake) powder&water aqua, etc.
"The effect of free and liposome encapsulated clodronate on the hepatic mononuclear phagocyte system in the rat." Clinical & Experimental Immunology, 99(2): pp.269-275 (1995).
Demographic and clinical characteristics of study population and the chemotherapeutic agents n Chemotherapeutic agents Patients 28 Sex (M/F) 6/22 Age (years), 52.3[+ or -]9.6 mean[+ or -]SD Cancer related 22 Breast cancer 9 Vinorelbine, docetaxel, clodronate, ietrozole, trastuzumab, capecitabine paclitaxel, dexamethasone sodium phosphate, gemcitabine, cisplatin Colorectal cancer 7 5-FU, leucovorin oxaliplatin, cisplatin, docetaxel, bevacizumab, irinotecan Gastric cancer 2 5-FU, leucovorin, cisplatin, docetaxel Other malignancies Methotrexate, cytarabine, ifosfamide, mesna, etoposide Noncancer related 6 M, male; F, female; FU, fluorouracil.
Bisphosphonates are mainly of two sub classes, non Nitrogen containing like Etidronate, Clodronate, Tiludronate and Nitrogen containing bisphosphonates Pamidronate, Nerid-ronate, Olpadronate, Alendronate, Ibandronate, Risedronate.
All bisphosphonates showed a significantly increased percentage change in BMD at the lumbar spine compared to calcium except clodronate. Pamidronate with calcium and Vitamin D analogs showed improved BMD in comparison to clodronate with calcium (mean difference [MD], 9.84; 95% credibility interval [CrI], 1.06-19.70).
Intravenous clodronate in the treatment of reflex sympathetic dystrophy syndrome.
Mitani, "Clodronate inhibits PGE2 production in compressed periodontal ligament cells," Journal of Dental Research, vol.
Chang, "Effects of clodronate on early alveolar bone remodeling and root resorption related to orthodontic forces: a histomorphometric analysis," American Journal of Orthodontics and Dentofacial Orthopedics, vol.
Since murine monocytes and other indigenous phagocytic cells are responsible for poor engraftment, several targeted techniques aimed at their eradication were developed such as the use of anti-murine SIRP[alpha], CD47, or Ncf1 knockout, and clodronate liposomes [42-44].
(37) Indeed, apoptotic Sm/RNP-reactive B cells are found in splenic MZ in 56R mice when macrophages are depleted by clodronate liposome (Fig.
Herein, we employed clodronate liposome (Clod Lipo) and anti-Gr-1 mAb strategies to modulate the presence and function of [Gr-1.sup.+] bone marrow-derived myeloid populations in bleomycin-challenged mice.
Selective SMLN macrophage in vivo depletion, using liposomes containing the proapoptotic agent clodronate, resulted in decreased Pg-induced alveolar bone in vivo resorption.