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1. An instrument other than a watch for measuring or indicating time, especially a mechanical or electronic device having a numbered dial and moving hands or a digital display.
2. A biological clock.
v. clocked, clocking, clocks
To register or record with a mechanical device: clocked the winds at 60 miles per hour.

clock′er n.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


A gene on chromosome 4q12 that encodes a ubiquitously expressed human homolog of the mouse clock gene, which forms a heterodimer with ARNTL and activates E-box element transcription of several circadian clock proteins (e.g., PER1 and PER2). CLOCK is highly expressed in the suprachiasmatic nucleus.

Molecular pathology
CLOCK-ARNTL double mutations in the PAS domains result in syngernistic desensitisation to high levels of CRY on repression of CLOCK-ARNTL transcriptional activity of PER1, disrupting circadian rhythmicity.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


A device for measuring time.

biological clock

1. An internal system in organisms that influences behavior in a rhythmic manner. Functions such as growth, feeding, secretion of hormones, the rate of drug action, the wake-sleep cycle, the menstrual cycle, and reproduction coincide with certain external events such as day and night, the tides, and the seasons. Biological clocks appear to be set by environmental conditions in some animals, but if these animals are isolated from their environment they continue to function according to the usual rhythm. A gradual change in environment does produce a gradual change in the timing of the biological clock. See: circadian; maladaptation to night work; zeitgeber
2. A colloquial term for the decrease in fertility that accompanies aging, particularly as women approach the age of 35.
Medical Dictionary, © 2009 Farlex and Partners

Patient discussion about clock

Q. How do you wake up in the morning if your narcolepsy is so severe you can't hear the alarm clock, phone ring? biggest problem is sleep paralysis, can't wake up. Late for work, everything, life is suffering because of severity. Have tried ritalin, natural supplements, hypnosis therapy, Provigal, antidepressants, nothing seems to work. Employer thinks it's an excuse, friends are irritated, I'm at my wits end. Life is spent sleeping more than awake.

A. Narcolepsy cannot yet be cured. But EDS and cataplexy, the most disabling symptoms of the disorder, can be controlled in most patients with drug treatment. Often the treatment regimen is modified as symptoms change. For decades, doctors have used central nervous system stimulants-amphetamines such as methylphenidate, dextroamphetamine, methamphetamine, and pemoline-to alleviate EDS and reduce the incidence of sleep attacks. For most patients these medications are generally quite effective at reducing daytime drowsiness and improving levels of alertness. However, they are associated with a wide array of undesirable side effects so their use must be carefully monitored. Common side effects include irritability and nervousness, shakiness, disturbances in heart rhythm, stomach upset, nighttime sleep disruption, and anorexia. For full article: Hope this helps.

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References in periodicals archive ?
Real estate investment trust Urstadt Biddle Properties Inc (NYSE:UBA) (NYSE:UBP) announced on Friday that it has purchased the Bernards Square Medical Office Building in Bernardsville, New Jersey and the Clockwork Childcare Center in Chester, New Jersey for a combined price of USD6.45m, excluding closing costs.
He makes her wear a necklace of clockwork pieces around her throat, which is also the photo that graces the book cover.
Wind her up, set her off on a pre-arranged course, and she'll perform a particular duty like clockwork until it's time to stop.
Sonically, Clockwork Radio are particularly un-obvious and the results are at times spectacular.
Clockwork Services had entered into a Company Voluntary Arrangement (CVA) with creditors on March 1, 2010, but at the beginning of September, directors realised that the company was about to breach a condition of the CVA and sought advice on the best way forward.
Centrica is buying Clockwork through its North American unit Direct Energy.
A Clockwork Orange was turned into a film in 1971 by director Stanley Kubrick and director Phil Swinburne says the People's Theatre production had borrowed many elements of the cult film.
Despite the chaotic scenes a Clockwork Orange spokesman heralded its promotion - where the cost of the item is based on the time of purchase - a massive success.
It "extends the reach of art but also complicates and burdens the enterprise of art with new, self-conscious standards." Meese guns for his greats: "My biggest goal is not only to direct in Bayreuth but to make A Clockwork Orange II, Zardoz II, The Damned II ..." These are impossible sequels.
West Midlands IT firm Clockwork Software Systems has hit a new milestone - despite losing an important client in the form of Powertrain, the engine and gearbox business of collapsed MG Rover.
A CLOCKWORK ORANGE - The Loft Theatre, Leamington, until Saturday.
In the movie A Clockwork Orange a young man seeks to create as much pain, angst and chaos as possible, and in turn tails into a state of harmony, I mean, he made love with two chicks.