clobetasone


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clobetasone

A steroid drug used externally for skin and non-infective eye inflammation. A brand name is Cloburate and, in conjunction with an antibitic and an antifungal drug, Trimovate.

antiinflammatory drug 

A drug which inhibits or suppresses most inflammatory responses of an allergic, bacterial, traumatic or anaphylactic origin, as well as being immunosuppressant. They include the corticosteroids (e.g. betamethasone, dexamethasone, fluorometholone, hydrocortisone acetate, loteprednol etabonate, prednisolone, rimexolone, triamcinolone). They are sometimes combined with an antibiotic drug (e.g. betamethasone combined with neomycin or sulfacetamide, dexamethasone combined with neomycin or polymyxin B). Corticosteroids have side effects, such as enhancing the activity of herpes simplex virus, fungal overgrowth, raising intraocular pressure or cataract formation.There are other antiinflammatory drugs that are non-steroidal (NSAID) and have little toxicity. They act mainly by blocking prostaglandin synthesis. These include diclofenac sodium, flurbiprofen sodium, indomethacin, ketorolac, nepafenac and oxyphenbutazone. See immunosuppressants; steroid.
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It transpired that it was prescribed as an alternative to clobetasone cream (a steroid of moderate potency) which was out of stock at that time.
Moderately low-potency steroids (triamcinolone, clobetasone, hydrocortisone, mometasone) have similar success compared to a highly potent steroid (betamethasone) (Level 2b, Grade B).
All patients received clobetasone eye drops for 1 month in a tapered dose as follows: 1 drop 4 times a day for the first week, 1 drop 3 times a day for the second week, 1 drop twice a day for the third week, and 1 drop once a day for the last week.
She had a number of positives including cetearyl alcohol, sodium metabisulphite, and clobetasone butyrate.
* Our patient was instructed to apply a topical clobetasone butyrate 0.05% cream twice a day.
Remission and relapse of chronic plaque psoriasis treat: once a week with clobetasone propionate occlude with hydrocolloid dressing versus twice daily treatment with clobetasone propionate alone.
The study found that in the United Kingdom, the prescribing ratio of emollients to topical steroids was almost 15 to 1, with the majority of steroid prescriptions being for a moderate potency drug (clobetasone butyrate, which is marketed as Eumovate).
Moderately low-potency steroids (tramcinolone, clobetasone, hydrocortisone, mometasone) may have the same successful results as a highly potent steroid (bethametasone).