(1) Clinically significant bleeding
following a dental procedure has been defined as bleeding that continues beyond 12 hours, causes the patient to call or return to the dental practice or other provider, results in the development of a large hematoma or bruising within the oral soft tissues, or requires a blood transfusion.
It has been shown to be less effective in reducing clinically significant bleeding
from SRMD than H2RAs (5) in a recent, large metaanalysis.
It's unclear whether any of our research definitions of clinically significant bleeding
have ever been validated as clinically important to our patients.
No incidence of clinically significant bleeding
was noted in either phase.
Clinically significant bleeding
in incurable cancer patients: effectiveness of hemostatic radiotherapy.