clinically significant bleeding


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clinically significant bleeding

Bleeding that causes hemodynamic instability (blood pressure less than 100 mm Hg or pulse more than 100 beats per min) or requires a transfusion of more than 2 units of blood in 24 hours.
See also: bleeding
References in periodicals archive ?
This review was undertaken in order to investigate current evidence behind their potential to prevent clinically significant bleeding in SRMD.
Effient plus ASA, however, produced higher rates of clinically significant bleeding than clopidogrel plus ASA (see Bleeding).
Specifically, rivaroxaban 15 mg once daily in combination with single antiplatelet therapy significantly reduced the rate of clinically significant bleeding by 41 per cent (relative risk reduction; equivalent to 9.
Eltrombopag (Promacta) reduced the odds of bleeding by 76% and of clinically significant bleeding by 65%, vs.
No incidence of clinically significant bleeding was noted in the preguidelines or postguidelines phase.

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