clinical significance

clinical significance

A change in a patient’s/subject's clinical status that is regarded as important, whether or not it is due to an intervention in the context of a clinical trial. The phrase clinical significance should not be used unless it is operationally defined.

clinical significance

Medtalk A conclusion that an intervention has an effect of practical meaning to Pts and health care providers; even though an intervention is found to have a statistically significant effect, this effect might not be clinically significant
References in periodicals archive ?
They also instructed the company to identify and consider the various types of reasons for catheter failure, and to show the clinical significance of this endpoint.
The FDA said the measures demonstrating improved sleep are of unclear clinical significance.
The medical textbook uses 275 color illustrations and 700 real-life rhythm strips to explain the science and clinical significance of arrhythmias, and connects electrocardiogram findings with physical exam and laboratory data to arrive at the correct diagnosis for a patient.
The clinical significance of these outcomes is further shown by a high responder rate on both corneal (at four weeks) and conjunctival (at three months) staining.
The clinical significance of this reduction in extraction temperature remains uncertain, and no clinical outcomes are reported.
Clinical significance of thyroid uptake on F18-fluorodeoxyglucose positron emission tomography.
The increased size of the aortic root is a new finding and one for which the clinical significance remains unclear.
Despite these associations, the clinical significance of anti-Ro52 antibodies remains controversial [8].
In the article titled "Expression and Clinical Significance of Cancer Stem Cell Markers CD24, CD44, and CD133 in Pancreatic Ductal Adenocarcinoma and Chronic Pancreatitis" [1], the affiliation listed for Dr.
IEFs were classified into three categories: (l) findings-with mild or no clinical significance, (2) findings with possible clinical significance, and (3) clinically significant findings.
Hence searching for a high-efficient and effective laboratory method is of great clinical significance to the diagnosis of bacterial infection.10 This study provides a scientific guidance for the clinical diagnosis and treatment of pediatric infectious diseases of newborns through investigating the values of serum PCT, CRP and WBC levels in the diagnosis of pediatric infectious diseases.

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