clinical sensitivity

clin·i·cal sen·si·tiv·i·ty

test positivity in disease; ability of a test to correctly identify disease.
See also: diagnostic sensitivity.

clin·i·cal sen·si·tiv·i·ty

(klin'i-kăl sen'si-tiv'i-tē)
The frequency of positive test results in patients with the disease (true-positive results).
Synonym(s): diagnostic sensitivity.
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References in periodicals archive ?
Receiver Operating Characteristic (ROC) curve shows the relationship between clinical sensitivity and specificity for every possible cut-off for a test or a combination of tests.
??Constellation said DermTech's offers a pipeline of dermatology-focussed diagnostic tests with clinical sensitivity, improved patient comfort due to non-invasive sample collection and meaningful cost savings for payors.
In 2010, in an effort to improve clinical sensitivity in diagnosing BD, revised diagnostic criteria were proposed by the international criteria for BD.[2] These criteria included oral aphthosis, genital ulcers, ocular manifestations, skin lesions, vascular manifestations of different sizes in various organs, central nervous system involvement, and positive pathergy test.
"Currently, the clinical sensitivity of EFIRM to detect patients with NSCLC is limited by the percentage of tumours containing either or both of the two variants, which is estimated at 27 per cent of NSCLC tumours," explained co-author Wu-Chou Su from the College of Medicine of the National Cheng Kung University in Taiwan.
In addition, clinical sensitivity is reduced in individuals with a small organism burden, such as in children, individuals with HIV infection, and in individuals with extrapulmonary TB (EPTB) infection.
Even though molecular assays have better clinical sensitivity, it is still imperative that good clinical samples be collected.
Analysis of variance tests were performed to compare clinical sensitivity with different disease stages.
The Sofia RSV assay employs advanced lateral flow and immunofluorescence technologies to provide enhanced clinical sensitivity for RSV.
Search terms for influenza were as follows: "influenza, human" [Medical Subject Heading (MeSh)] OR "influenza A virus" [MeSh] OR "influenza B virus" [MeSh] OR "influenza" or "flu." Search terms for the tests included "RT-PCR," "reverse transcription polymerase chain reaction," "culture," direct florescent antibody," "DFA," "rapid diagnostic test." Search terms for clinical sensitivity included "sensitivity," "test characteristics," "diagnostic test characteristics," and "test performance characteristics." We hand-searched bibliographies of included studies and recent narrative reviews of influenza diagnostic tests for additional relevant studies.
In-house validation study showed a 100% clinical sensitivity and specificity, with an LLOD of approximate 0.5 ng/ml.
Assay h-tTG IgA h-tTG IgG chemiluminescent 1.9-4965.5CU 3.75-2560.0CU immunoassay fluoroenzyme 0.1-128 U/mL 0.5-600 U/mL immunoassay Assay DGP IgA DGP IgG chemiluminescent 5.2-2367.3CU 2.8-1936.7CU immunoassay fluoroenzyme 0.2-213 U/mL 0.2-192 U/mL immunoassay Table 2: Clinical sensitivity and specificity.

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