Strict glycaemic control also delays the onset of microalbuminuria, the progression of microalbuminuria to clinical proteinuria, and the development of nephropathy in patients with either type 1 or type 2 diabetes.
Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes.
In turn, albuminuria was broken down into two further categories: microalbuminuria with ACR values between 20 and 300 mg/g and clinical proteinuria indicated by ACR values above 300 mg/g (20).
Seventy-five percent of patients presented with albuminuria the first morning of admission to the reanimation unit (67% microalbuminuria and 8% clinical proteinuria).
MICRO-HOPE, a subset of the HOPE trial, studied ramipril (Altace) 10 mg/d vs placebo in 2437 patients with diabetes who did not have clinical proteinuria
. Patients were aged 55 years or older and had either a previous cardiovascular event or at least 1 other cardiovascular risk factor.
is indicated at a ratio result of 300 mg/g (33.9 mg/mmol) or greater.
If excretion is lower than 20 microgram/min, the patient is considered to have normo-albuminuria and if excretion is higher than 200 microgram/min, he is considered to have Macro-albuminuria or clinical proteinuria
. Micro-albuminuria should be present in at least two or three urine samples collected over a period of several months.
Effect of captopril on progression to clinical proteinuria
in patients with insulin-dependent diabetes mellitus and microalbuminuria.
The most common causes of clinical proteinuria
are those without clinical significance.
Improved biuret procedure for routine determination of urinary total proteins in clinical proteinuria
. Clin Chem 1975;21:398-401.
If excretion is lower than 20 microgm/min, the patient is considered to have normoalbuminuria, and if excretion is higher than 200 microgm/min, he is considered to have macroalbuminuria or clinical proteinuria
. Micro-albuminuria should be present in at least two of three urine samples collected over a period of several months.