clinical benefit response

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clinical benefit response

Abbreviation: CBR

An improvement in at least one important symptom or element of the quality of life of a cancer patient that directly results from treatment, without any decline in any other element of the patient's quality of life.

Patient care

Some cancers are not curable or responsive to treatment with surgery, radiation, or chemotherapy. However, one or more of their most distressing symptoms may be manageable, e.g. alleviation of pain by therapy. Palliation of pain, nausea, or breathlessness, even in the absence of cure, is a clinically beneficial goal of treatment for some incurable tumors, such as cancers of the pancreas.